Electrochemical and kinetic study of oxygen in a perfluorotributylamine emulsion
Electrochemical and kinetic study of oxygen in a perfluorotributylamine emulsion
复制标题
全氟三丁胺乳液中氧的电化学和动力学研究
DOI：
10.1016/0003-2670(83)80071-3
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发表时间：
1983
影响因子：
6.2
通讯作者：
J. Georges
中科院分区：
文献类型：
--
作者：
A. Berthold;J. Georges
可以通过库仑分析法和极谱法测定用作血液替代品的全氟三丁胺乳液中的氧含量。乳液的吸氧量（25°C 和 P O 2= 760 mm Hg 时为 4.3× 10− 3 mol l− 1 或 11 ml-%）大约是水的三倍。表面活性剂在滴汞电极上的吸附改变了电化学参数 E 1 2、α 和 k 3。氧和过氧化氢的扩散系数（比率 2.6）之间的显着差异似乎是由于氧分子从全氟三丁胺液滴中的喷射以及液滴中过氧化氢分子的不溶性所致。通过停流分光光度法估计这些液滴释放氧气的恒定速率为 10 4 s− 1。该恒定速率似乎与全氟三丁胺液滴的粒径（0.2 μm）和扩散系数（1.6×10− 6 cm 2 s− 1）有关。
Oxygen can be determined in a perfluorotributylamine emulsion used as a blood substitute by coulometry and polarography. The oxygen uptake of the emulsion (4.3× 10− 3 mol l− 1 or 11 ml-% at 25° C and P O 2= 760 mm Hg) is about three times greater than that of water. The adsorption of surfactant on a dropping mercury electrode changes the electrochemical parameters E 1 2, α and k 3. The marked difference between the diffusion coefficients of oxygen and hydrogen peroxide (ratio 2.6) seems to be proceed from the ejection of oxygen molecules from the perfluorotributylamine droplets and from the insolubility of hydrogen peroxide molecules in the droplets. The constant rate of oxygen release by these droplets was estimated to be 10 4 s− 1 by a stopped-flow spectrophotometric method. This constant rate seems to be linked with the particle diameter (0.2 μm) and the diffusion coefficient in the perfluorotributylamine droplets (1.6× 10− 6 cm 2 s− 1).