Innervation of the nucleus of the solitary tract and the dorsal vagal nucleus by thyrotropin-releasing hormone-containing raphe neurons

Innervation of the nucleus of the solitary tract and the dorsal vagal nucleus by thyrotropin-releasing hormone-containing raphe neurons
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含促甲状腺激素释放激素的中缝神经元对孤束核和迷走神经背核的神经支配

DOI:
10.1016/0006-8993(86)90338-0
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发表时间:
1986
期刊:
影响因子:
2.9
通讯作者:
M. Brownstein
M. Brownstein
中科院分区:
医学3区
文献类型:
--
作者:
M. Palkovits;É. Mezey;R. Eskay;M. Brownstein

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孤束核和迷走神经背核由中缝尾侧核发出的含促甲状腺素释放激素(TRH)的纤维支配。垂直方向的纤维横断后,水平刀切在延髓,TRH染色消失,迷走神经核,而它增加横断的神经纤维腹侧的刀切。TRH阳性细胞主要位于中缝苍白核和中缝隐核。含TRH的纤维在中缝背侧走行,并在其吻端进入迷走背侧复合体。然后它们转向尾部并向侧面发出分支。在奥贝水平的尾部,几个含TRH的纤维穿过中央管。中缝以外的区域(下丘脑或其他吻侧区、延髓腹外侧区、脑神经)的细胞对孤束核和迷走神经背核的TRH神经支配一定贡献很小,因为切断上述所有可能的连接的各种刀切并不改变这些迷走神经核的TRH神经支配模式或TRH浓度。
The nucleus of the solitary tract and the dorsal vagal nucleus are richly innervated by thyrotropin-releasing hormone (TRH)-containing fibers arising from the caudal raphe nuclei. After transection of vertically oriented fibers by a horizontal knife-cut in the medulla oblongata, TRH-staining disappeared from the vagal nuclei while it increased in transected nerve fibers ventral to the knife-cut. TRH-containing cells are mainly located in the nucleus raphe pallidus and raphe obscurus. TRH-containing fibers run dorsally within the raphe and enter the dorsal vagal complex at its rostral tip. Then they turn caudally and send branches laterally. Immediately caudal to the level of the obex, several TRH-containing fibers cross over the central canal. Cells in regions other than the raphe (hypothalamus or other rostral areas, ventrolateral medulla, cranial nerves) must contribute little to the TRH innervation of the nucleus of the solitary tract and dorsal vagal nucleus, since various knife-cuts transecting all above possible connections did not alter the TRH innervation pattern or TRH concentrations of these vagal nuclei.
免疫反应性人类生长激素样物质和促甲状腺激素释放激素在大鼠中枢神经系统中的分布:它们在同一神经元中共存的证据。
DOI: 10.1210/endo-112-3-877
发表时间: 1983
期刊: Endocrinology
影响因子: 4.8
作者:
Lechan,RM;Molitch,ME;Jackson,IM
通讯作者: Jackson,IM