Microscopy of living bone marrow in situ.
Microscopy of living bone marrow in situ.
复制标题
活体骨髓原位显微镜检查。
DOI：
10.1182/blood.v38.1.87.87
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发表时间：
1971
期刊：
影响因子：
20.3
通讯作者：
W. Younker
中科院分区：
文献类型：
--
作者：
R. McCuskey;S. McClugage;W. Younker
设计了一个腔室，用于原位活体骨髓的慢性显微检查。如果要发生正常的造血，腔隙内邻近组织的金属含量似乎是至关重要的，因为过量的金属会导致细胞过少的胶质性骨髓再生。当金属量减少时，相对正常的骨髓再生进入腔室。最常见的是组织学上类似于黄色骨髓，但偶尔观察到高度活跃的骨髓。微血管系统的初步检查证实了先前的报道，即窦一般排列在围绕单个或簇状脂肪细胞和造血细胞的相互连接的多边形网络中。窦状动脉内有明确的内皮。未见“窦间毛细血管”。
A chamber has been designed to permit chronic microscopic examination of living bone marrow in situ. The amount of metal adjacent to the tissue within the gap of the chamber appears to be critical if normal hemopoiesis is to occur, since excessive metal resulted in the regeneration of a hypocellular, gelatinous marrow. When the amount of metal was reduced, relatively normal marrow regenerated into the chamber. Most frequently this histologically resembled yellow marrow but on occasion highly active marrow was observed. Preliminary examination of the microvascular system confirmed previous reports that sinusoids generally were arranged in interconnecting polygonal networks surrounding individual or clusters of fat and hemopoietic cells. The sinusoids were lined by a definite endothelium. No "intersinusoidal capillaries" were observed.