Testing in EHS: What is the Current Status of Experimentation?
Testing in EHS: What is the Current Status of Experimentation?
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EHS 测试：实验现状如何？
DOI：
10.1109/nano.2011.6144671
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发表时间：
2011
期刊：
影响因子：
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通讯作者：
Nurmi,JamesT
中科院分区：
文献类型：
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作者：
Baer,DonaldR;Karakoti,AjayS;Munusamy,Prabhakaran;Thrall,BrianD;Pounds,JoelG;Teeguarden,JustinG;Amonette,JamesE;Orr,Galya;Tratnyek,PaulG;Nurmi,JamesT
本文探讨了与纳米颗粒在环境中的行为及其对人类健康的潜在影响有关的一些基本和实际问题。在我们的研究中，我们探索了纳米颗粒与环境中污染物的反应行为，纳米颗粒如何响应其环境和时间而变化，以及纳米颗粒如何与各种类型的生物系统相互作用。很明显，研究人员经常低估了为特定类型的测试或应用制备和提供良好表征的纳米颗粒的困难。困难出现在从不理解什么赋予颗粒的“纳米”特性到不知道次要物质对高表面积材料的性质的影响的范围内的区域。我们的一些冒险和不幸作为其中一些问题的例子，因为它们涉及到为生物学研究提供定义良好的粒子。
This paper explores some of the fundamental and practical issues related to the behavior of nanoparticles in the environment and their potential impacts on human health. In our research we have explored the reactive behaviors of nanoparticles with contaminants in the environment, how nanoparticle change in response to their environment and time, and how nanoparticles interact with biological systems of various types. It has become apparent that researchers often underestimate the difficulties of preparing and delivering well characterized nanoparticles for specific types of testing or applications. Difficulties arise in areas that range from not understanding what imparts the “nano” character of a particle to not knowing the impacts of minor species on the properties of high surface area materials. Some of our adventures and misadventures serve as examples of some of these issues as they relate to providing well defined particles for biological studies.