3D Printed Bionic Nanodevices.
3D Printed Bionic Nanodevices.
复制标题
3D打印的仿生纳米电视。
DOI：
10.1016/j.nantod.2016.04.007
复制
发表时间：
2016-06
期刊：
影响因子：
17.4
通讯作者：
McAlpine MC
中科院分区：
文献类型：
--
作者：
Kong YL;Gupta MK;Johnson BN;McAlpine MC
三维交织生物和功能材料的能力可以创造出具有独特和引人注目的几何形状、特性和功能的仿生设备。事实上，将高性能有源设备与生物学相结合可以影响许多领域，包括再生生物电子医学、智能假肢、医疗机器人和人机界面。生物学，从DNA和蛋白质的分子尺度，到组织和器官的宏观尺度，都是三维的，往往是柔软和可拉伸的，并且对温度敏感。这使得大多数生物平台与已经为功能电子开发和优化的制造和材料加工方法不兼容，这些方法通常是平面的，刚性的和脆性的。已经制定了一些策略来克服这些二分法。一种特别新颖的方法是使用基于挤压的多材料3D打印，这是一种提供自由形状制造策略的增材制造技术。这种方法解决了上述二分法：(1)使用3D打印和成像进行定制，分层和交织的设备架构；(2)采用纳米技术作为引入高性能材料的可行途径，这些材料有可能表现出在散装材料中所没有的特性；(3) 3D打印一系列软性和纳米级材料，使各种高质量功能纳米材料与生物学相结合。此外，3D打印是一个多尺度平台，允许整合功能纳米级油墨，打印微尺度特征，并最终创建宏观尺度设备。这种3D打印、新型纳米材料特性和“活体”平台的融合可能会使下一代仿生系统成为可能。在这篇综述中，我们强调了纳米材料的独特性能与基于挤压的3D打印技术的多功能性的协同集成，以交织纳米材料和制造新型仿生装置。
The ability to three-dimensionally interweave biological and functional materials could enable the creation of bionic devices possessing unique and compelling geometries, properties, and functionalities. Indeed, interfacing high performance active devices with biology could impact a variety of fields, including regenerative bioelectronic medicines, smart prosthetics, medical robotics, and human-machine interfaces. Biology, from the molecular scale of DNA and proteins, to the macroscopic scale of tissues and organs, is three-dimensional, often soft and stretchable, and temperature sensitive. This renders most biological platforms incompatible with the fabrication and materials processing methods that have been developed and optimized for functional electronics, which are typically planar, rigid and brittle. A number of strategies have been developed to overcome these dichotomies. One particularly novel approach is the use of extrusion-based multi-material 3D printing, which is an additive manufacturing technology that offers a freeform fabrication strategy. This approach addresses the dichotomies presented above by (1) using 3D printing and imaging for customized, hierarchical, and interwoven device architectures; (2) employing nanotechnology as an enabling route for introducing high performance materials, with the potential for exhibiting properties not found in the bulk; and (3) 3D printing a range of soft and nanoscale materials to enable the integration of a diverse palette of high quality functional nanomaterials with biology. Further, 3D printing is a multi-scale platform, allowing for the incorporation of functional nanoscale inks, the printing of microscale features, and ultimately the creation of macroscale devices. This blending of 3D printing, novel nanomaterial properties, and ‘living’ platforms may enable next-generation bionic systems. In this review, we highlight this synergistic integration of the unique properties of nanomaterials with the versatility of extrusion-based 3D printing technologies to interweave nanomaterials and fabricate novel bionic devices.