Examining whether the information-motivation-behavioral skills model predicts medication adherence for patients with a rare disease.
Examining whether the information-motivation-behavioral skills model predicts medication adherence for patients with a rare disease.
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DOI：
10.2147/ppa.s115272
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发表时间：
2017
影响因子：
2.2
通讯作者：
Carpenter DM
中科院分区：
文献类型：
--
作者：
Alexander DS;Hogan SL;Jordan JM;DeVellis RF;Carpenter DM
信息-动机-行为技能（IMB）模型已被用于解释和促进糖尿病和艾滋病毒患者的药物依从性。本研究的目的是检查IMB模型是否预测血管炎患者的药物依从性。成人血管炎患者（n=228）在基线和3个月随访时完成在线问卷调查。通过线性回归分析，确定信息和动机对服药依从性的直接影响（P<0.05）。中介分析使用自举方法被用来测试是否行为技能显着介导的信息和动机对药物依从性的影响。参与者报告了高水平的信息（M=4.0;标准差[SD]=0.68），中等水平的动机（M=2.7; SD=1.00）和高水平的行为技能（M=4.1; SD=0.74）。在回归模型中，只有行为技能（B=0.38; P<0.001）与药物依从性显著相关;然而，中介分析显示，行为技能显著中介信息和动机对药物依从性的影响。结果支持IMB假设的信息，动机，行为技能和药物依从性之间的关系，在我们的样本。研究结果表明，供应商应与血管炎患者合作，增加他们的药物相关技能，以提高药物依从性。
The information–motivation–behavioral skills (IMB) model has been used to explain and promote medication adherence among patients with diabetes and HIV. The objective of this study was to examine whether the IMB model predicted medication adherence among vasculitis patients. Adult vasculitis patients (n=228) completed online questionnaires at baseline and 3-month follow-up. Linear regressions were calculated to determine the direct effects of information and motivation on medication adherence (P<0.05). A mediation analysis using a bootstrapping approach was used to test whether behavioral skills significantly mediated the effect of information and motivation on medication adherence. Participants reported high levels of information (M=4.0; standard deviation [SD]=0.68), moderate levels of motivation (M=2.7; SD=1.00), and high levels of behavioral skills (M=4.1; SD=0.74). In the regression model, only behavioral skills (B=0.38; P<0.001) were significantly associated with medication adherence; however, mediation analysis revealed that behavioral skills significantly mediated the effects of information and motivation on medication adherence. The results support the IMB-hypothesized relationships between information, motivation, behavioral skills, and medication adherence in our sample. Findings suggest that providers should work with vasculitis patients to increase their medication-related skills to improve medication adherence.