Copper(I) oxide catalyzed n-arylation of Azoles and Amines with arylboronic acid at room temperature under base-free conditions
Copper(I) oxide catalyzed n-arylation of Azoles and Amines with arylboronic acid at room temperature under base-free conditions
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DOI：
10.1055/s-2008-1032184
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发表时间：
2008-03-03
影响因子：
2.6
通讯作者：
Balasubrahmanyarn, Vura
中科院分区：
文献类型：
--
作者：
Sreedhar, Bojja;Venkanna, Gopaladasu T.;Balasubrahmanyarn, Vura
在无碱条件下，异相氧化铜(I)在甲醇中实现了氮唑和胺与芳基硼酸的N-芳基化反应。产物N-芳基氮唑和N-芳基胺的分离产率很高。各种芳基硼酸和胺被转化为相应的N-芳基氮唑和N-芳胺，证明了反应的准确性。
N-Arylation of azoles and amines with arylboronic acids was efficiently carried out with heterogeneous copper(I) oxide in methanol at room temperature under base-free conditions. The products N-arylazoles and N-arylamines were isolated in good to excellent yields. A variety of arylboronic acids and amines were converted to the corresponding N-arylazoles and N-arylamines, demonstrating the versatality of the reaction.