Sedentary screen time and left ventricular structure and function: the CARDIA study.
Sedentary screen time and left ventricular structure and function: the CARDIA study.
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DOI：
10.1249/mss.0b013e3182a4df33
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发表时间：
2014-02
影响因子：
4.1
通讯作者：
Lewis CE
中科院分区：
文献类型：
--
作者：
Gibbs BB;Reis JP;Schelbert EB;Craft LL;Sidney S;Lima J;Lewis CE
久坐不动的屏幕时间（看电视或使用电脑）预测心血管结果独立于中度和剧烈的体力活动，并可能通过久坐行为的不良后果影响左心室结构和功能。确定久坐屏幕时间是否与左心室结构和功能的测量相关。2010-2011年，年轻人冠状动脉风险发展（CARDIA）研究通过问卷调查测量了2，854名年龄在43-55岁之间的黑人和白色参与者的屏幕时间，并通过超声心动图测量了左心室结构和功能。广义线性模型评估了更高类别的屏幕时间中超声心动图测量的横截面趋势，并根据人口统计学、吸烟、酒精和身体活动进行了调整。进一步的模型调整了潜在的中间因素（血压、抗高血压药物使用、糖尿病和体重指数（BMI））。筛查时间与左心室质量（LVM）之间的关系在黑人与白人中不同。在白人中，在调整身高、人口统计学和生活方式变量后，筛查时间越长，左心室质量越大（P<0.001）。当调整血压、抗高血压药物使用和糖尿病（P=0.008）时，筛查时间和左心室质量之间的相关性持续存在，但不需要额外调整BMI（P=0.503）。观察到筛选时间与指数为2.7的LVM、相对壁厚和质量体积比之间存在类似的关系。筛查时间与黑人的左心室结构或两个种族组的左心室功能无关。在白色成年人中，久坐不动的屏幕时间与更大的左心室质量相关，这种关系在很大程度上可以用更高的总体肥胖来解释。黑人中缺乏相关性支持久坐屏幕行为的心血管后果的潜在质的差异。
Sedentary screen time (watching TV or using a computer) predicts cardiovascular outcomes independently from moderate and vigorous physical activity and could impact left ventricular structure and function through the adverse consequences of sedentary behavior. To determine whether sedentary screen time is associated with measures of left ventricular structure and function. The Coronary Artery Risk Development in Young Adults (CARDIA) Study measured screen time by questionnaire and left ventricular structure and function by echocardiography in 2,854 black and white participants, aged 43–55 years, in 2010–2011. Generalized linear models evaluated cross-sectional trends for echocardiography measures across higher categories of screen time and adjusting for demographics, smoking, alcohol, and physical activity. Further models adjusted for potential intermediate factors (blood pressure, antihypertensive medication use, diabetes, and body mass index (BMI). The relationship between screen time and left ventricular mass(LVM) differed in blacks vs. whites. Among whites, higher screen time was associated with larger LVM (P<0.001), after adjustment for height, demographics, and lifestyle variables. Associations between screen time and LVM persisted when adjusting for blood pressure, antihypertensive medication use, and diabetes (P=0.008) but not with additional adjustment for BMI (P=0.503). Similar relationships were observed for screen time with LVM indexed to height2.7, relative wall thickness, and mass-to-volume ratio. Screen time was not associated with left ventricular structure among blacks or left ventricular function in either race group. Sedentary screen time is associated with greater LVM in white adults and this relationship was largely explained by higher overall adiposity. The lack of association in blacks supports a potential qualitative difference in the cardiovascular consequences of sedentary screen-based behavior.