The Future of Adult Cardiac Assist Devices: Novel Systems and Mechanical Circulatory Support Strategies
The Future of Adult Cardiac Assist Devices: Novel Systems and Mechanical Circulatory Support Strategies
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DOI：
10.1016/j.ccl.2011.08.013
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发表时间：
2011-11-01
影响因子：
2.4
通讯作者：
Dowling, Robert D.
中科院分区：
文献类型：
--
作者：
Bartoli, Carlo R.;Dowling, Robert D.
近年来，机械循环支持的广泛成功促进了许多可植入设备的发展，以治疗晚期心力衰竭。重要的是要提高对新型器械系统、其功能机制以及对患者管理的影响的认识。本文讨论了正在开发或正在临床试验的器械。器械分为标准完全支持、微创完全支持、部分支持（旋转泵）、部分支持（反搏器械、右心室辅助器械和全人工心脏）。考虑植入策略、作用机制、耐久性、有效性、血液相容性和人为因素。新的策略卸载衰竭的心脏的可行性进行了研究。
The recent, widespread success of mechanical circulatory support has prompted the development of numerous implantable devices to treat advanced heart failure. It is important to raise awareness of novel device systems, the mechanisms by which they function, and implications for patient management. This article discusses devices that are being developed or are in clinical trials. Devices are categorized as standard full support, less-invasive full support, partial support: rotary pumps, partial support: counterpulsation devices, right ventricular assist device, and total artificial heart. Implantation strategy, mechanism of action, durability, efficacy, hemocompatibility, and human factors are considered. The feasibility of novel strategies for unloading the failing heart is examined.