EDOTn and MIM, new peptide backbone protecting groups
EDOTn and MIM, new peptide backbone protecting groups
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DOI：
10.1002/bip.20823
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发表时间：
2008-01-01
期刊：
影响因子：
2.9
通讯作者：
Albericio, Fernando
中科院分区：
文献类型：
--
作者：
Isidro-Llobet, Albert;Just-Baringo, Xavier;Albericio, Fernando
In recent years, backbone protection has allowed the synthesis of complex peptidic sequences of high interest by preventing chain aggregation and aspartimides formation. Nevertheless, the backbone protectors currently used have some drawbacks: they are difficult to remove and show high steric hindrance. The new backbone protectors presented in this study (EDOTn and MIM) represent an improvement in both aspects. (c) 2007 Wiley Periodicals, Inc.
