RESISTANCE TO OXYTETRACYCLINE, OXOLINIC ACID AND FURAZOLIDONE IN BACTERIA FROM MARINE-SEDIMENTS
RESISTANCE TO OXYTETRACYCLINE, OXOLINIC ACID AND FURAZOLIDONE IN BACTERIA FROM MARINE-SEDIMENTS
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DOI：
10.1016/0044-8486(92)90135-8
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发表时间：
1992-06-01
期刊：
影响因子：
4.5
通讯作者：
HORMAZABAL, V
中科院分区：
文献类型：
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作者：
NYGAARD, K;LUNESTAD, BT;HORMAZABAL, V
用土霉素(OTC)或恶唑酸(OXA)处理的沉积物被放置在海床上，为期一年。在测试期结束时，添加了OTC的沉积物中对OTC具有抗药性的细菌比例(SOT)(16%)比本底水平(5%)高出三倍多。对添加了OXA的沉积物(SOX)也发现了同样的趋势。SOT和SOX对OTC和OXA均存在交叉耐药。SOX对呋喃唑酮有很高的交叉耐药性(34%)，而SOT则没有观察到。
Sediments experimentally treated with oxytetracycline (OTC) or oxolinic acid (OXA) were placed on the seabottom for a period of 1 year. At the end of the test period the fraction of bacteria resistant to OTC in sediments to which OTC had been added (SOT) was more than three times higher (16%) than the background level (5%). The same tendency was found for the sediments to which OXA was added (SOX). Cross-resistance towards OTC and OXA was found both in SOT and SOX. A high level of cross-resistance (34%) towards furazolidone was found for SOX, but was not observed for SOT.