Comparison of anxiety-like behavior in adolescent and adult Sprague-Dawley rats.
Comparison of anxiety-like behavior in adolescent and adult Sprague-Dawley rats.
复制标题
青少年和成年斯普拉格道利大鼠的焦虑样行为的比较。
DOI：
10.1037/0735-7044.119.6.1477
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发表时间：
2005
期刊：
影响因子：
--
通讯作者：
Slawecki,CraigJ
中科院分区：
文献类型：
--
作者：
Slawecki,CraigJ
The conditions under which age differences in anxiety are observed in rodents are unclear. These studies explored the influence of test condition on anxiety-like behavior in adolescent and adult rats using the light-dark box. Behavior was assessed under different illumination levels (30 or 60 lux) and after brief stress (restraint or bright light). Anxiety-like behavior did not differ in the 30-lux test but was increased in adolescents in the 60-lux test. Restraint increased anxiety-like behavior in adolescents, resulting in elevated anxiety-like behavior relative to adults. Bright light decreased anxiety-like behavior, possibly because of negative contrast or novelty-induced anxiolysis. These studies demonstrate that adolescents display increased anxiety-like behavior when test conditions are more aversive and following exposure to stress.(PsycINFO Database Record (c) 2016 APA, all rights reserved)
