Quality of life in tuberculosis: A review of the English language literature
Quality of life in tuberculosis: A review of the English language literature
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DOI：
10.1007/s11136-004-0374-1
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发表时间：
2004-12-01
影响因子：
3.5
通讯作者：
Diette, GB
中科院分区：
文献类型：
--
作者：
Chang, B;Wu, AW;Diette, GB
前言：结核病（TB）研究主要集中在临床结果；很少有研究调查结核病对患者生活质量（QOL）的影响。方法：使用特定MESH术语对已发表的医学文献进行系统回顾：[结核病]和1 -[结果]，2 -[结果评估]，3[生活质量]，4 -[情绪障碍]，5 -[成本和成本分析]，6 -[宗教]，7 -[感知]，8[社会支持]，9 -[乐观]，10 -[压力]，11 -[体征和症状]和12 -[疾病成本]。这产生了1972篇文章；60篇文章符合纳入标准并进行了审查。结果：结核病躯体症状已经得到了很好的研究，但没有研究对身体功能或一般健康观念的影响。患者往往对自己的诊断感到担忧、沮丧或失望，但尚不清楚情绪健康如何随着治疗而改变。确诊的患者找工作的可能性更小，工作和照顾家庭的能力也更弱。结核病给穷人造成了最大的经济负担。在发展中国家，患者及其家属受到社会的排斥，家庭有时也会排斥患者；结核病在发达国家的社会污名程度尚不清楚。结论：对结核病生活质量的研究相对较少，发达国家的研究更少。更好的了解可能有助于改善治疗方案，坚持治疗，以及结核病患者的功能和福祉。
Introduction: Tuberculosis ( TB) studies have concentrated on clinical outcomes; few studies have examined the impact of TB on patients' quality of life (QOL). Methods: A systematic review of published medical literature using specific MESH terms: [ Tuberculosis] and 1 - [ Outcome], 2 - [ Outcome Assessment], 3 [ Quality of Life], 4 - [ Mood Disorder], 5 - [ Cost and Cost Analysis], 6 - [ Religion], 7 - [ Perception], 8 [ Social Support], 9 - [ Optimism], 10 - [ Stress], 11 - [ Signs and Symptoms], and 12 - [ Cost of Illness]. This yielded 1972 articles; 60 articles met inclusion criteria and were reviewed. Results: TB somatic symptoms have been well studied, but there were no studies of effects on physical functioning or general health perceptions. Patients tend to be worried, frustrated, or disappointed by their diagnosis, but it is unknown how emotional health changes with treatment. Diagnosed patients are less likely to find work, and less able to work and care for their families. TB creates the greatest financial burden on the poor. In developing countries, patients and their families are ostracized by society, and families sometimes ostracize patients; the extent of TB's social stigma in the developed countries is unknown. Conclusion: There has been relatively little research on TB QOL and even less in developed countries. A better understanding may help improve treatment regimens, adherence to treatment, and functioning and well-being of people with TB.