Invited commentary: Personality phenotype and mortality--new avenues in genetic, social, and clinical epidemiology.
Invited commentary: Personality phenotype and mortality--new avenues in genetic, social, and clinical epidemiology.
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特邀评论：人格表型和死亡率——遗传、社会和临床流行病学的新途径。
DOI：
10.1093/aje/kwt169
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发表时间：
2013
影响因子：
5
通讯作者：
Chapman,BenjaminP
中科院分区：
文献类型：
--
作者：
Chapman,BenjaminP
在本期杂志中，Jokela等人（Am J Epidemiol.2013;178（5）：667-675）通过使用“个体参与者荟萃分析”设计，详细审查了人格表型与全因死亡率之间的关联。在7个人口统计学和人格测量方法不同的大型队列中，他们发现五因素（或“大五”）人格模型的4个维度存在不同的前瞻性关联，但“大五”维度的前瞻性关联是稳健和一致的。Jokela等人对这一主题的长期研究提出了一个重要的感叹号，并直接或间接地暗示了这一研究路线的新途径。我认为以下3个领域特别值得进一步研究：遗传学在人格和健康研究中的作用;人格在健康方面的社会不平等中的作用;以及Jokela等人的工作的健康政策和临床意义，包括人格表型在个性化医疗发展中的潜在作用。
In this issue of theJournal, Jokela et al. (Am J Epidemiol.2013;178(5):667–675) scrutinize the association between personality phenotype and all-cause mortality in remarkable detail by using an “individual-participant meta-analysis” design. Across 7 large cohorts varying in demographics and methods of personality measurement, they find varying prospective associations for 4 dimensions of the five-factor (or “Big Five”) model of personality, but robust and consistent prospective associations for Big Five dimension of “conscientiousness.” Jokela et al. place an important exclamation point on a long era of study of this topic and hint directly and indirectly at new avenues for this line of research. I consider the following 3 areas particularly rife for further inquiry: the role of genetics in personality and health studies; the role of personality in social inequalities in health; and the health policy and clinical implications of work like that of Jokela et al., including the potential role of personality phenotype in the evolution of personalized medicine.