ONCHOCERCA-SIMULIUM COMPLEXES .I. TRANSMISSION OF FOREST AND SUDAN-SAVANNA STRAINS OF ONCHOCERCA VOLVULUS FROM CAMEROON BY SIMULIUM DAMNOSUM FROM VARIOUS WEST AFRICAN BIOCLIMATIC ZONES
ONCHOCERCA-SIMULIUM COMPLEXES .I. TRANSMISSION OF FOREST AND SUDAN-SAVANNA STRAINS OF ONCHOCERCA VOLVULUS FROM CAMEROON BY SIMULIUM DAMNOSUM FROM VARIOUS WEST AFRICAN BIOCLIMATIC ZONES
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DOI：
10.1080/00034983.1966.11686422
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发表时间：
1966-01-01
影响因子：
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通讯作者：
MOORE, PJ
中科院分区：
文献类型：
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作者：
DUKE, BOL;LEWIS, DJ;MOORE, PJ
来自喀麦隆林区的螺旋体微丝虫在西非许多地区的森林和几内亚-稀树草原地区的丹诺姆吸虫中发育良好，但在苏丹-稀树草原地区的达姆诺姆吸虫种群中几乎没有发展。相反，来自喀麦隆苏丹-稀树草原地区的旋毛虫微丝虫在苏丹-稀树草原地区的丹诺萨姆幼虫中发育良好，而在几内亚-稀树草原和林区的苍蝇中几乎或没有发育。在西非，有两种旋毛虫和两种主要生理类型的丹诺氏链霉菌。这些寄生虫-病媒复合体形成了两个基本上不同的寄生虫-媒介复合体，一个延伸到森林和几内亚草原地区，另一个仅限于苏丹-稀树草原地区。这些发现的意义特别参考不同区域的人类盘尾丝虫的临床模式进行了讨论，可能会发现这两种旋毛虫菌株在致病性、在人类宿主中的寿命和对化疗药物的敏感性方面是不同的。
Microfilariae of Onchocerca volvulus from forest areas of Cameroon developed well in Simulium damnosum from the forest and Guinea-savanna zones of many parts of West Africa, but they showed little or no development in S. damnosum populations from sites in Sudan-savanna zones. Conversely, microfilariae of O. volvulus from the Sudan-savanna area of Cameroon developed well in S. damnosum from Sudan-savanna zones, but showed little or no development in flies from Guinea-savanna and forest zones. There are, in West Africa, 2 strains of O. volvulus and 2 main physiological forms of S. damnosum. with some minor variations, and that these are coupled to form 2, largely distinct, parasite-vector complexes, one extending over the forest and Guinea-savanna zones, and the other confined to the Sudan-savanna zones. The implications of these findings are discussed with particular reference to the clinical pattern of human onchocerciasls in the different zones, and the 2 strains of O. volvulus may be found to differ in pathogenicity, in length of life in the human host, and in susceptibility to chemotherapeutic agents.