COVID-19 Infection in Iranian Children: A Case Series of 9 Patients

COVID-19 Infection in Iranian Children: A Case Series of 9 Patients
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DOI:
10.32598/jpr.8.2.139
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发表时间:
2020-04-01
影响因子:
0.4
通讯作者:
Rezai, Mohammad Sadegh
Rezai, Mohammad Sadegh
中科院分区:
其他
文献类型:
--
作者:
Rahimzadeh, Golnar;Noghabi, Mina Ekrami;Rezai, Mohammad Sadegh

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背景:新冠肺炎是由一种新型冠状病毒引起的急性呼吸道传染病。世界卫生组织(WHO)已宣布这种感染为全球大流行。与成人相比,儿童这种疾病的发病率、严重性和预后可能不同。在此,我们报告9例伊朗新冠肺炎感染的儿科患者。病例介绍:我们报告9例在伊朗不同医院收治的新冠肺炎患儿。6名患者为男性。最小的两岁,最大的十岁。所有儿童都至少有一名受感染的家庭成员。所有病例均有发热、寒战、肌痛、咳嗽、呼吸急促、回缩和爆裂等症状。我们的患者没有一例出现腹泻、呕吐或流鼻涕的症状。3例出现白细胞减少和淋巴细胞减少。在3例患者中检出新冠肺炎核糖核酸。所有病例均检测到C反应蛋白和血沉升高。2例乳酸脱氢酶升高。所有病例均给予支持护理和抗生素治疗,6天内出院,一般情况良好。结论:无基础疾病的新冠肺炎肺炎患儿预后良好。我们的患者在不需要LPN/r、利巴韦林或机械通气的情况下康复。
Background: COVID-19 is an acute infectious respiratory disease caused by a novel coronavirus. The World Health Organization (WHO) has declared the infection a global pandemic. The incidence, severity, and prognosis of this disease are likely to be different in children compared with adults. Herein we present 9 pediatric patients with COVID-19 infection in Iran.Case Presentation: We present 9 pediatric cases of COVID-19 admitted to different hospitals in Iran. Six patients were male. The youngest was two years old and the oldest one ten years. All children had at least one infected family member. Fever, chills, myalgia, cough, tachypnea, retraction, and crackle were common in all cases. None of our patients presented with diarrhea, vomiting, or a runny nose. Three cases had leukopenia and lymphopenia. COVID-19 RNA was identified in three cases. In all cases, elevated C-reactive protein and erythrocyte sedimentation rate were detected. Two cases had a high level of lactate dehydrogenase. All cases received supportive care and antibiotic therapy and were discharged within six days with a good general condition.Conclusions: COVID-19 pneumonia prognosis is good in children with no underlying diseases. Our patients recovered without the need for LPN/r, ribavirin, or mechanical ventilation.