On the role of the SMA in the discrete sequence production task: a TMS study
On the role of the SMA in the discrete sequence production task: a TMS study
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DOI：
10.1016/s0028-3932(01)00221-4
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发表时间：
2002-01-01
期刊：
影响因子：
2.6
通讯作者：
van Honk, J
中科院分区：
文献类型：
--
作者：
Verwey, WB;Lammens, R;van Honk, J
参与者练习了两个离散的六键序列，总共进行了 420 次试验。 I x 6 序列具有独特的按键顺序，而 2 x 3 序列则涉及重复三键片段。两个序列在序列中间都显示出较长的键间间隔，表明分层序列控制，因为不仅 2 x 3 而且 I x 6 序列都作为两个连续的运动块执行。此外，两个序列的第二部分的执行速度都比第一部分快。这支持了早期的概念，即运动处理器执行熟悉的运动块的元素，认知处理器触发这些运动块或单独的序列元素。辅助运动区 (SMA) 的低频、离线经颅磁刺激 (TMS) 抵消了在所有序列位置进行按键练习的正常改善。总之，这些结果与这样的观点相一致：通过适度的练习，SMA 会执行由其他大脑结构连接起来的短序列片段。 (C) 2002 Elsevier Science Ltd. 保留所有权利。
Participants practiced two discrete six-key sequences for a total of 420 trials. The I x 6 sequence had a unique order of key presses while the 2 x 3 sequence involved repetition of a three-key segment. Both sequences showed a long interkey interval halfway the sequence indicating hierarchical sequence control in that not only the 2 x 3 but also the I x 6 sequence was executed as two successive motor chunks. Besides, the second part of both sequences was executed faster than the first part. This supports the earlier notion of a motor processor executing the elements of familiar motor chunks and a cognitive processor triggering either these motor chunks or individual sequence elements. Low-frequency, off-line transcranial magnetic stimulation (TMS) of the supplementary motor area (SMA) counteracted normal improvement with practice of key presses at all sequence positions. Together, these results are in line with the notion that with moderate practice, the SMA executes short sequence fragments that are concatenated by other brain structures. (C) 2002 Elsevier Science Ltd. All rights reserved.