Thiol-ene oligomers as dental restorative materials
Thiol-ene oligomers as dental restorative materials
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DOI：
10.1016/j.dental.2005.04.002
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发表时间：
2005-12-01
期刊：
影响因子：
5
通讯作者：
Bowman, CN
中科院分区：
文献类型：
--
作者：
Carioscia, JA;Lu, H;Bowman, CN
Objective.本工作的目的是使硫醇-烯单体预反应以产生反应性硫醇或乙烯基（烯）官能化的低聚物，并研究这些材料作为新型牙科修复材料的用途。研究集中在低聚硫醇-烯材料作为牙科修复树脂的应用上，与单体硫醇-烯体系相比，特别是与目前的基于二甲基丙烯酸酯的体系相比，低聚硫醇-烯材料具有塔聚合收缩和聚合应力。使用三丁基-1，3，5-三嗪-2，4，6-三酮（TATATO）、正丙烷三（3-巯基丙酸酯）（三硫醇）和季戊四醇四巯基丙酸酯（四硫醇）通过光聚合产生反应性硫醇官能化的低聚物。对Bis-GMA/TEGDMA、低聚物和单体硫醇-烯体系进行了动力学和力学研究。更具体地，评价聚合收缩和应力、聚合动力学、玻璃化转变温度、弯曲强度和弯曲模量。在评估时，低聚硫醇-烯体系的聚合应力与单体硫醇-烯体系所表现出的应力相比显著降低多达33%，并且相对于当前基于二甲基丙烯酸酯的牙科修复材料，应力降低多达92%。此外，单体和低聚硫醇-烯树脂的弯曲强度和模量没有显著差异。低聚硫醇-烯体系由于聚合收缩和应力的显著降低而提供了作为替代牙科修复树脂的潜力，白色保留了基于单体的硫醇-烯树脂的机械性能。(C)2005年牙科材料学院。由爱思唯尔有限公司出版。保留所有权利。
Objective. The aim of this work was to prereact thiol-ene monomers to create reactive thiol or vinyl (ene)-functionalized oligomers, and to investigate the use of these materials as novel dental restorative material. Investigation has focused on the application of oligomeric thiol-ene materials as dental restorative resins with tower polymerization shrinkage and polymerization stress as compared to monomeric thiol-ene systems and particularly with respect to current dimethacrylate-based systems.Methods. Reactive thiol-functionalized oligomers were created via photopolymerization using triattyl-1,3,5-triazine-2,4,6-trione (TATATO), trimethylolpropane tris(3-mercaptopropionate) (trithiol) and pentaerythritol tetramercaptopropionate (tetrathiol). Kinetic and mechanical investigation of Bis-GMA/TEGDMA, and oligomeric and monomeric thiol-ene systems were conducted. More specifically, polymerization shrinkage and stress, polymerization kinetics, glass transition temperature, flexural strength and flexural modulus were evaluated.Results. Upon evaluation, the polymerization stress of oligomeric thiol-ene systems was dramatically reduced by as much as 33% when compared with the stress exhibited by monomeric thiol-ene systems and as much as a 92% reduction in stress relative to the current dimethacrylate-based dental restorative materials. Furthermore, the flexural strength and modulus of the monomeric and oligomeric thiol-ene resins were not significantly different.Significance. Oligomeric thiol-ene systems offer potential as alternative dental restorative resins due to the significant reduction in polymerization shrinkage and stress white retaining the mechanical properties of monomer-based thiol-ene resins. (C) 2005 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.