Cu-catalyzed C-H amination of hydrofullerenes leading to 1,4-difunctionalized fullerenes.
Cu-catalyzed C-H amination of hydrofullerenes leading to 1,4-difunctionalized fullerenes.
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DOI：
10.1021/ol403573r
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发表时间：
2014-01
期刊：
影响因子：
5.2
通讯作者：
Weili Si;Shi-Han Lu;M. Bao;N. Asao;Yoshinori Yamamoto;T. Jin
中科院分区：
文献类型：
--
作者：
Weili Si;Shi-Han Lu;M. Bao;N. Asao;Yoshinori Yamamoto;T. Jin
报道了一种新颖高效的铜催化单官能氢富勒烯C-H胺化反应合成1，4-双官能富勒烯的方法。在温和的反应条件下，以较高的产率合成了一系列具有不同单胺键合物的1，4-富勒烯衍生物。控制实验表明，反应通过形成富勒烯单价基作为关键中间体，然后与胺自由基偶联进行。
A novel and highly efficient Cu-catalyzed C-H amination of the monofunctionalized hydrofullerenes for the synthesis of 1,4-difunctional fullerenes has been reported. A new series of 1,4-fullerene derivatives having various monoamine addends were synthesized in good to high yields under mild reaction conditions. The controlled experiments revealed that the reaction proceeds through the formation of a fullerene monoradical as a key intermediate followed by coupling with an amine radical.