Left atrium: the last bulwark before overt heart failure
Left atrium: the last bulwark before overt heart failure
复制标题
DOI：
10.1007/s10741-016-9589-9
复制
发表时间：
2017-01-01
影响因子：
4.6
通讯作者：
Mondillo, Sergio
中科院分区：
文献类型：
--
作者：
Cameli, Matteo;Mandoli, Giulia Elena;Mondillo, Sergio
射血分数保留性心力衰竭（HF）是近年来出现的一个重要的公共卫生问题。它代表了门诊环境中最常见的HF类型，并且已被认为是与射血分数降低（EF）形式不同的实体。在HFpEF中，从舒张功能障碍（DD）的第一阶段开始，左心房（LA）在保持患者良好心室功能和无症状状态方面的作用一直受到越来越多的关注。舒张期的非侵入性和完整的超声心动图评价不能免除准确分析的LA大小，主要是LA体积，及其功能，特别是斑点跟踪超声心动图（STE）的LA心肌变形。本文综述了左心房在DD和HFpEF中不断扩大的作用，以及在各种情况下对其进行全面评估的重要性，从诊断到与主要心血管事件的相关性。
Heart failure (HF) with preserved ejection fraction (HFpEF) has emerged as an important public health issue in recent years. It represents the most common type of HF in ambulatory setting, and it has been recognized as a different entity from the reduced ejection fraction (EF) form. In HFpEF, continuous growing attention has been focused on the role of the left atrium (LA) in preserving good ventricular function and asymptomatic condition of the patient since the very first stages of diastolic dysfunction (DD). Non-invasive and complete echocardiographic evaluation of diastolic phase cannot exempt from accurately analyzed LA size, mostly LA volume, and its function, in particular LA myocardial deformation by speckle tracking echocardiography (STE). This review examines the expanding role of the LA in DD and HFpEF and the importance of its complete assessment in various settings, from diagnosis to correlation with major cardiovascular events.