The psychoses of epilepsy
The psychoses of epilepsy
复制标题
癫痫的精神病
DOI：
10.1136/jnnp.70.5.708a
复制
发表时间：
2001
期刊：
影响因子：
--
通讯作者：
Perminder S. Sachdev
中科院分区：
文献类型：
--
作者：
Perminder S. Sachdev
Toone1最近的社论强调了我们对癫痫和精神病之间关系的理解的不足。虽然这种联系的某些方面现在比斯莱特的经典报告时更好地建立起来，但对这些精神病背后的病理生理过程的见解似乎进展甚微。在我看来，一个主要的原因是，研究的重点更多地放在慢性精神分裂症样精神病上，而不是发作性精神病上，后者更有可能产生可检验的假设。
可以认为，发作后精神病提供了最好的机会，以检查一些病理生理机制的基础关系。这些精神病发生在一般在精神病前状态下接受检查的患者中，可能在患者住院期间发展。
The recent editorial by Toone1 serves to highlight the deficiencies in our understanding of the relation between epilepsy and psychosis. Although some aspects of this association are now better established than they were at the time of Slater's classic report,2 insights into the pathophysiological processes underlying these psychoses seem to have advanced very little. A major reason for this, in my opinion, is that the greater focus of research has been on chronic schizophrenia-like psychoses rather than on the episodic psychoses, which are more likely to yield testable hypotheses.
It can be argued that postictal psychoses present the best opportunity to examine some of the pathophysiological mechanisms that underlie the relation. These psychoses occur in patients who have generally been examined in their prepsychotic states, are likely to develop in hospital while the patient is being …