Associations between liking for fat, sweet or salt and obesity risk in French adults: a prospective cohort study.
Associations between liking for fat, sweet or salt and obesity risk in French adults: a prospective cohort study.
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DOI：
10.1186/s12966-016-0406-6
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发表时间：
2016-07-04
期刊：
影响因子：
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通讯作者：
Méjean C
中科院分区：
文献类型：
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作者：
Lampuré A;Castetbon K;Deglaire A;Schlich P;Péneau S;Hercberg S;Méjean C
个人感官喜好似乎是饮食摄入量的重要决定因素，并可能因此影响体重状况。横断面研究表明，对脂肪的喜好与体重状况呈正相关，而对盐和甜的喜好的结果则模棱两可。此外，饮食摄入对解释这种关系的贡献尚未得到研究。我们调查了5年以上成年人对脂肪、糖或盐的感官喜好与肥胖发病之间的前瞻性关联，以及饮食摄入量的中介作用。我们前瞻性地研究了24,776名参加nutrinet - sant<s:1>队列研究的法国成年人的肥胖风险。分别使用经过验证的基于网络的问卷和24小时记录在基线时评估喜欢分数和饮食数据。在5年的时间里，每年使用基于网络的问卷收集自我报告的人体测量数据。通过按性别分层的多变量Cox比例风险模型，并根据社会人口统计学和生活方式因素进行调整，评估喜欢脂肪、甜或盐的四分位数与肥胖风险之间的关联，以及饮食的中介效应。在两性中，对脂肪的感官喜好与肥胖风险增加相关(四分位数4与四分位数1的风险比，男性：HRQ4vs.Q1 = 2.39 （95% CI 1.39,4.11) P-trend = 0.0005，女性：HRQ4vs.Q1 = 2.02 (1.51,2.71) P-trend = <0.0001）。饮食摄入解释了32%的男性和52%的女性在肥胖中喜欢脂肪的总体变化。对甜味的感官喜爱与肥胖风险降低有关(男性：HRQ4vs.Q1 = 0.51 （0.31,0.83) P-trend = 0.01，女性：HRQ4vs.Q1 = 0.72 (0.54,0.96) P-trend = 0.035）。没有发现喜欢吃盐和肥胖风险之间的显著联系。与喜欢甜食和盐不同，更喜欢脂肪似乎是肥胖的主要风险因素，这在很大程度上可以通过饮食摄入来解释。我们的研究结果强调了在肥胖预防中需要把感觉喜好放在中心位置。
Individual sensory liking appears to be an important determinant of dietary intake and may consequently influence weight status. Cross-sectional studies have shown positive association between fat liking and weight status and equivocal results regarding salt and sweet liking. Moreover, the contribution of dietary intake to explain this relationship has not been studied yet. We investigated the prospective association between sensory liking for fat, sweet or salt and the onset of obesity over 5 years in adults, and the mediating effect of dietary intake. We prospectively examine the risk of obesity among 24,776 French adults participating in the NutriNet-Santé cohort study. Liking scores and dietary data were assessed at baseline using a validated web-based questionnaire and 24 h records, respectively. Self-reported anthropometric data were collected using web-based questionnaire, each year during 5 years. Associations between quartiles of liking for fat, sweet or salt and obesity risk, and the mediating effect of diet were assessed by multivariate Cox proportional hazards models stratified by gender, adjusted for sociodemographic and lifestyle factors. In both genders, sensory liking for fat was associated with an increased risk of obesity (hazard ratios for quartile 4 compared to quartile 1, men: HRQ4vs.Q1 = 2.39 (95 % CI 1.39,4.11) P-trend = 0.0005, women: HRQ4vs.Q1 = 2.02 (1.51,2.71) P-trend = <0.0001). Dietary intake explained 32 % in men and 52 % in women of the overall variation of liking for fat in obesity. Sensory liking for sweet was associated with a decreased risk of obesity (men: HRQ4vs.Q1 = 0.51 (0.31,0.83) P-trend = 0.01, women: HRQ4vs.Q1 = 0.72 (0.54,0.96) P-trend = 0.035). No significant association between salt liking and the risk of obesity was found. Unlike sweet and salt liking, higher liking for fat appears to be a major risk factor of obesity, largely explained by dietary intake. Our findings emphasize the need to centrally position sensory liking in obesity prevention.