CORRELATION BETWEEN SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY FINDINGS AND VISUAL OUTCOME AFTER PRIMARY RHEGMATOGENOUS RETINAL DETACHMENT REPAIR
CORRELATION BETWEEN SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY FINDINGS AND VISUAL OUTCOME AFTER PRIMARY RHEGMATOGENOUS RETINAL DETACHMENT REPAIR
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DOI：
10.1097/iae.0b013e3182180114
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发表时间：
2012-01-01
影响因子：
3.3
通讯作者：
Gabrieli, Corrado Balacco
中科院分区：
文献类型：
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作者：
Gharbiya, Magda;Grandinetti, Francesca;Gabrieli, Corrado Balacco
目的：将孔源性视网膜脱离成功修复后的术后视觉结果与中央凹的频域光学相干断层扫描 (SD-OCT) 结果相关联。横断面观察性研究。方法：纳入 35 例术前黄斑部孔源性视网膜脱离（12 只眼）和黄斑部孔源性视网膜脱离（23 只眼）的患者，因原发性孔源性视网膜脱离而接受巩膜扣带手术。早期治疗糖尿病视网膜病变研究当天进行了最佳矫正视力测量、显微视野检查和SD-OCT检查。使用 SD-OCT 测量中心凹中心视网膜厚度、中心 1 mm 子视野厚度和外核层厚度。评估视网膜前膜、视网膜内液和视网膜下液的存在或不存在。还评估了外界膜、内/外节段连接处和中间线的状态，并判断为破坏或完整。分析了 SD-OCT 结果与术后最佳矫正视力或中央 12 度视网膜敏感性之间的相关性。结果：外核层厚度是唯一显着的 SD-OCT 视网膜测量值，与术后最佳矫正视力（r = 0.61；P < 0.001）和中央 12 度视网膜敏感性（r = 0.53；P = 0.001）。在 SD-OCT 成像结果中，外界膜、内/外节段连接处和中间线的状态以及视网膜内液体的存在与最佳矫正视力结果显示出显着的高度相关性（r = -0.60；P < 0.001，r = -0.63；P < 0.001，r = -0.66；P < 0.001，r = -0.50；P = 0.002，分别）或术后视网膜敏感性（分别为 r = -0.59；P < 0.001，r = -0.61；P < 0.001，r = -0.66；P < 0.001，r = -0.50；P = 0.002）。多变量分析显示，外核层厚度和中间线的状态是视力结果最重要的预测因素（分别为P，0.001和P，0.001）。结论：本研究表明，不仅外界膜和内/外段连接处的状态，而且中间线的完整性和外核层厚度的变化可能是解剖学上成功的孔源性视网膜脱离修复术后视力结果的重要预测因素。视网膜 32:43-53, 2012
Purpose: To correlate the postoperative visual outcome with the spectral-domain optical coherence tomography (SD-OCT) findings in the fovea after successful rhegmatogenous retinal detachment repair. Cross-sectional, observational study.Methods: Thirty-five patients with preoperative macula-on rhegmatogenous retinal detachment (12 eyes) and macula-off rhegmatogenous retinal detachment (23 eyes) who underwent scleral buckling surgery for primary rhegmatogenous retinal detachment were recruited. Early Treatment Diabetic Retinopathy Study best-corrected visual acuity measurement, microperimetry, and SD-OCT examination were performed on the same day. Foveal center retinal thickness, central 1-mm subfield thickness, and outer nuclear layer thickness were measured using SD-OCT. The presence or absence of epiretinal membrane, intraretinal fluid, and subretinal fluid was assessed. The status of the external limiting membrane, inner/outer segment junction, and intermediate line was also evaluated and judged as disrupted or complete. The correlations between SD-OCT findings and either postoperative best-corrected visual acuity or retinal sensitivities for central 12 degrees were analyzed.Results: The outer nuclear layer thickness was the only significant SD-OCT retinal measurement strongly correlated with both postoperative best-corrected visual acuity (r = 0.61; P < 0.001) and retinal sensitivities for central 12 degrees (r = 0.53; P = 0.001). Among the SD-OCT imaging findings, status of the external limiting membrane, inner/outer segment junction, and intermediate line and the presence of intraretinal fluid showed a significantly high correlation either with best-corrected visual acuity outcome (r = -0.60; P < 0.001, r = -0.63; P < 0.001, r = -0.66; P < 0.001, and r = -0.50; P = 0.002, respectively) or with postoperative retinal sensitivities (r = -0.59; P < 0.001, r = -0.61; P < 0.001, r = -0.66; P < 0.001, r = -0.50; P = 0.002, respectively). Multivariate analysis showed that the outer nuclear layer thickness and the status of the intermediate line were the most important predictors of visual outcome (P, 0.001 and P, 0.001, respectively).Conclusion: This study showed that not only the status of the external limiting membrane and the inner/outer segment junction but also the integrity of the intermediate line and the outer nuclear layer thickness changes may be important predictors of postoperative visual outcome after anatomically successful rhegmatogenous retinal detachment repair. RETINA 32:43-53, 2012