EFFECTS OF AMBIENT-TEMPERATURES ON INDUCTION OF TRANSMISSIBLE GASTROENTERITIS IN FEEDER PIGS
EFFECTS OF AMBIENT-TEMPERATURES ON INDUCTION OF TRANSMISSIBLE GASTROENTERITIS IN FEEDER PIGS
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DOI：
10.1128/iai.21.3.747-752.1978
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发表时间：
1978-01-01
影响因子：
3.1
通讯作者：
KODAMA, Y
中科院分区：
文献类型：
--
作者：
SHIMIZU, M;SHIMIZU, Y;KODAMA, Y
本试验研究了环境温度对饲养猪传染性胃肠炎2-3个月的影响。年长的。猪保持在高温下(30。+-。2.学位。C)和暴露于强毒力的传染性胃肠炎病毒，在高温下维持期间没有表现出疾病的临床症状。环境温度的突然下降，无论是在接种病毒之前还是之后，都会导致暴露在病毒下的饲养猪患上严重的疾病。猪在低温(4。+-)条件下的连续维护。1.学位。C)倾向于在一定程度上减少迹象的出现频率，与该温度下的维护期的长短成比例。猪的饲养温度在20。+-之间波动。2.学位。和4.+-。1.学位。C每24小时出现一次重度腹泻。在温度波动的情况下，猪的临床体征持续时间比在恒定低温下的猪长。从有临床症状和无临床症状的猪采集的血清中，除1例外，均可检测到抗传染性胃肠炎病毒抗体。从出现临床症状的猪身上收集的血清中获得的抗体效价比那些遭受感染但没有症状的猪的血清中的抗体滴度略高。
Experiments were carried out to investigate the effects of ambient temperatures on the induction of transmissible gastroenteritis in feeder pigs 2-3 mo. old. Pigs maintained at a high temperature (30 .+-. 2.degree. C) and exposed to the virulent transmissible gastroenteritis virus did not show clinical signs of the disease during their maintenance at the high temperature. A sudden decrease in the ambient temperature, either before and after virus inoculation, induced severe disease in feeder pigs exposed to the virus. Continuous maintenance of pigs at the low temperature (4 .+-. 1.degree. C) tended to somewhat reduce the frequency of occurrence of signs in proportion to the length of the maintenance periods at that temperature. Pigs raised at temperatures that fluctuated between 20 .+-. 2.degree. and 4 .+-. 1.degree. C every 24 h developed profuse diarrhea. The duration of clinical signs was longer in pigs maintained under the fluctuating temperatures than in those at the constantly low temperature. With 1 exception, antibody against transmissible gastroenteritis virus was demonstrated in sera collected from pigs both with and without clinical signs. Antibody titers obtained were somewhat higher in sera collected from pigs that developed clinical signs than in those from pigs that endured the infection without showing signs.