Implantable left ventricular assist system.

Implantable left ventricular assist system.
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植入式左心室辅助系统。

DOI:
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发表时间:
2009
影响因子:
3.3
通讯作者:
C. Nojiri
C. Nojiri
中科院分区:
医学3区
文献类型:
--
作者:
C. Nojiri

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第一代脉冲植入式左心室辅助系统(LVAS)的第一次临床应用是在1980年中期,S作为移植的桥梁,推动了该领域从临床实验到治疗晚期心力衰竭患者的既定治疗选择。然而,随着更长期的经验的积累,技术上的限制已经浮出水面。这些问题包括血栓栓塞症并发症、感染、与移动部件相关的机械故障,以及植入式泵和经皮电缆的大尺寸。为了克服第一代搏动性左心辅助装置的局限性,1990年S提出了一种较小的旋转式血泵左心辅助装置,这些新一代的左心辅助装置正处于不同的开发和临床应用阶段。本文就可植入左冠状动脉的历史和现状作一综述。
The first clinical application of the first-generation pulsatile implantable left ventricular assist system (LVAS) was in the mid 1980 s as a bridge to transplantation and contributed to an advancement of this field from a clinical experiment to an established therapeutic option for treating advanced heart failure patients. However, there have been technological limitations that have surfaced as longer-term experience has been gained. These include a high incidence of thromboembolic complications, infection, mechanical failures associated with moving parts, and the large size of both implantable pump and percutaneous cable. In order to overcome the limitations of the first-generation pulsatile LVAS, a smaller rotary blood pump LVAS emerged as a possible alternative in the 1990 s and these new generation LVAS are in various stages of development and clinical application. This article reviews the history and current status of the implantable LVAS.
DOI: 10.1056/nejmoa012175
发表时间: 2001-11-15
影响因子: 158.5
作者:
Rose, EA;Gelijns, AC;Meier, P
通讯作者: Meier, P