LAYER-V IN RAT AUDITORY-CORTEX - PROJECTIONS TO THE INFERIOR COLLICULUS AND CONTRALATERAL CORTEX
LAYER-V IN RAT AUDITORY-CORTEX - PROJECTIONS TO THE INFERIOR COLLICULUS AND CONTRALATERAL CORTEX
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DOI：
10.1016/0378-5955(88)90047-0
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发表时间：
1988-07-01
期刊：
影响因子：
2.8
通讯作者：
WINER, JA
中科院分区：
文献类型：
--
作者：
GAMES, KD;WINER, JA
本研究比较了辣根过氧化物酶注射同侧下丘或听皮质后，成年大鼠听皮层投射到下丘的细胞和连合细胞在V层的形态和分布。这项工作的目标是确定V层的每一部分是否平等地参与两种投射，以及每条通路中的大脑皮层神经元是否相似。在高尔基-考克斯制剂中定义了神经元的类型，并与来自建筑定义的皮质区域41的逆行标记细胞的轮廓相匹配。下丘和连合神经元来自两个种群，它们在V层、体细胞区域和顶端树枝的形式上分布不同。皮质小丘神经元包括最大的锥体细胞，其充满的顶端树突粗壮地上升到第二层或更远。连合细胞较小，具有更多的异质性。顶端树突通常不会延伸到IV层以上，其中一些细胞可能是非锥体细胞。小锥体细胞和倒锥体细胞投射到对侧皮质，但不投射到下丘。两个系统都有中等大小的锥体细胞投射。此外，在第V层和第III层中，某些起源于骨痂的细胞在形态上是相似的。投射神经元出现。大多数皮质小球细胞位于V层更深的位置，那里的连合神经元较少。这些结果表明，投射到端脑和中脑靶点的传出细胞在形态上是不同的，在空间上是分离的。然而，连合投射在不同的皮质层包括相似的细胞。这些传出神经元的类型可能与它们的靶点比与它们的板层起源更密切相关。
This study compares the form and distribution within layer V of cells projecting to the inferior colliculus with that of commissural cells of origin in adult rat auditory cortex after horseradish peroxidase injections in the ipsilateral inferior colliculus or auditory cortex. The goal of this work was to determine whether every part of layer V participates equally in both projections, and if the cortial neurons in each pathway were similar. The types of neurones were defined in Golgi-Cox preparations and matched with the profiles of retrogradely labeled cells from architectonically defined cortical area 41. Inferior colliculus and commissural neurons from two populations that differ in their distribution in layer V, in somatic area, and in the form of their apical dendritic arbors. Corticocollicular neurons include the largest pyramidal cells, whose robustly filled apical dendrites ascend into layer II or farther. Commissural cells are smaller and have a more heterogeneous form. The apical dendrites do not usually extend above layer IV, and a few of these cells may be non-pyramidal. Small pyramidal cells and inverted pyramidal cells project to the opposite cortex, but not to the inferior colliculus. Medium-sized pyramidal cells project in both systems. In addition, certain callosal cells of origin in layers V and III were morphologically similar. projection neurons arise. Most corticocollicular cells lie deeper in layer V, where there are fewer commissural neurons. These findings suggest that the efferent projecting to telencephalic and mesencephalic targets are morphologically distinct and spatially segregated in layer V. However, the commissural projection includes similar cells in different cortical layers. The types of these efferent neurons may be more closely related to their target than to their laminar origin.