Withholding research results in academic life science - Evidence from a national survey of faculty

Withholding research results in academic life science - Evidence from a national survey of faculty
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DOI:
10.1001/jama.277.15.1224
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发表时间:
1997-04-16
影响因子:
120.7
通讯作者:
Louis, KS
Louis, KS
中科院分区:
医学1区
文献类型:
--
作者:
Blumenthal, D;Campbell, EG;Louis, KS

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目的.-确定学术生命科学家中隐瞒数据行为的普遍性和决定因素。设计.-对 1993 年获得美国国立卫生研究院资助最多的 50 所大学的 3394 名生命科学教职人员进行邮寄调查。参与者.-共有 2167 名教职人员对调查做出了答复,答复率为 64%。结果衡量标准。-受访者是否推迟发表其研究成果超过 6 个月以及受访者是否在过去 3 年内拒绝与其他大学科学家分享研究成果。结果 - 共有 410 名受访者 (19.8%) 表示,他们的研究成果在过去 3 年内至少有一次被推迟超过 6 个月的发表,以允许专利申请、保护其科学领先地位、减缓不良结果的传播、留出时间进行专利谈判或解决知识产权所有权纠纷。此外,181 名受访者 (8.9%) 表示,在过去 3 年中拒绝与其他大学科学家分享研究成果,在多变量分析中,参与学术与产业研究关系以及参与大学研究的商业化与出版延迟显着相关。比值比 (OR) 和 95% 置信区间 (Cls) 分别为 1.34 (1.07-1.59) 和 3.15 (2.88-3.41)。与拒绝分享结果相关的变量包括进行类似于人类基因组计划的研究(OR,2.09;95% CI,1.75-2.42)、发表率(OR,1.02;95% CI,1.01-1.03)以及参与研究商业化(OR,2.45;95% CI, 2.08-2.82).结论。-扣留研究成果在生命科学研究人员中并不是普遍现象,然而,扣留在最具生产力和创业精神的教师中更为常见。这些结果还表明,数据扣留已经影响了相当数量的生命科学教师,建议对数据扣留做法进行进一步研究。
Objectives.-To identify the prevalence and determinants of data-withholding behaviors among academic life scientists.Design.-Mailed survey of 3394 life science faculty in the 50 universities that received the most funding from the National Institutes of Health in 1993.Participants.-A total of 2167 faculty responded to the survey, a 64% response rate.Outcome Measures.-Whether respondents delayed publication of their research results for more than 6 months and whether respondents refused to share research results with other university scientists in the last 3 years.Results.-A total of 410 respondents (19.8%) reported that publication of their research results had been delayed by more than 6 months at least once in the last 3 years to allow for patent application, to protect their scientific lead, to slow the dissemination of undesired results, to allow time to negotiate a patent, or to resolve disputes over the ownership of intellectual property. Also, 181 respondents (8.9%) reported refusing to share research results with other university scientists in the last 3 years, in multivariate analysis, participation in an academic-industry research relationship and engagement in the commercialization of university research were significantly associated with delays in publication. Odds ratios (ORs) and 95% confidence intervals (Cls) were 1.34 (1.07-1.59) and 3.15 (2.88-3.41), respectively. Variables associated with refusing to share results were conducting research similar to the Human Genome Project (OR, 2.09; 95% CI, 1.75-2.42), publication rate (OR, 1.02; 95% CI, 1.01-1.03), and engagement in commercialization of research (OR, 2.45; 95% CI, 2.08-2.82).Conclusions.-Withholding of research results is not a widespread phenomenon among life-science researchers, However, withholding is more common among the most productive and entrepreneurial faculty, These results also suggest that data withholding has affected a significant number of life-science faculty and further study on data-withholding practices is suggested.