Impairments in activities of daily living in older Japanese men in hawaii and Japan.
Impairments in activities of daily living in older Japanese men in hawaii and Japan.
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DOI：
10.4061/2011/324592
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发表时间：
2011-01-01
影响因子：
4.7
通讯作者：
Ueshima, Hirotsugu
中科院分区：
文献类型：
--
作者：
Abbott, Robert D;Kadota, Aya;Ueshima, Hirotsugu
导论.在日本，高血压和吸烟是心血管疾病的主要危险因素，而在西方国家，更广泛的影响包括肥胖、糖尿病和高胆固醇血症。本文探讨是否不同的协会也出现在日常生活活动（ADL）的表现在老年日本男性在夏威夷和日本的重要。方法.从1995年到1999年，对夏威夷的1,893名男性和日本的543名男性进行了ADL（进食、排便、穿衣、洗澡和在房子周围走动）测量。从1990年到1993年测量了伴随的风险因素。结果在夏威夷，糖尿病使≥ 1 ADL受损的几率增加近1.5倍（P = 0.020）。日本没有类似的协会。相比之下，在日本，中风患者ADL受损的几率增加了5倍以上（P <0.001）。夏威夷的相关性明显较弱（P = 0.007）。在这两个队列中，既往饮酒与ADL受损的可能性更大相关。结论在遗传相似样本的比较中，研究结果表明，在日本和西方国家，与心血管疾病相关的风险因素的不同强度也可能包括与ADL受损相关的不同强度。
Introduction. Hypertension and cigarette smoking are dominant risk factors for cardiovascular disease in Japan while in westernized countries, broader effects encompass obesity, diabetes, and hypercholesterolemia. This paper examines whether different associations also appear important in the manifestation of activities of daily living (ADL) in older Japanese men in Hawaii and Japan. Methods. Measures of ADL (feeding, toileting, dressing, bathing, and walking around the house) were assessed from 1995 to 1999 in 1,893 men in Hawaii and 543 men in Japan. Concomitant risk factors were measured from 1990 to 1993. Results. In Hawaii, diabetes increased the odds of ≥1 ADL impairment nearly 1.5-fold (P = .020). A similar association was absent in Japan. In contrast, the odds of an ADL impairment in Japan was increased more than 5-fold in the presence of stroke (P < .001). The association in Hawaii was significantly weaker (P = .007). In both cohorts, past alcohol use was associated with a greater likelihood of ADL impairment. Conclusion. In this comparison of genetically similar samples, findings suggest that different strengths in risk factor associations with cardiovascular disease in Japan and westernized countries may also include different strengths in associations with impaired ADL.