DYNAMIC MECHANICAL PROPERTIES OF HUMAN BRAIN TISSUE
DYNAMIC MECHANICAL PROPERTIES OF HUMAN BRAIN TISSUE
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DOI：
10.1016/0021-9290(69)90079-7
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发表时间：
1969-01-01
影响因子：
2.4
通讯作者：
MELVIN, JW
中科院分区：
文献类型：
--
作者：
FALLENSTEIN, GT;HULCE, VD;MELVIN, JW
多年来，研究人员一直在研究与头部撞击有关的机械现象。关于大脑在头部撞击时的行为的一些理论来自这些研究，但关于大脑的整体力学特性的信息明显缺乏，而这些特性是评估这些理论所必需的。本文是提供此类信息的初步尝试。测定了人脑离体样品的动态复合剪切模量。在一个机电测试装置中，对八个大脑样本进行了谐振条件下的正弦剪切应力输入。试验确定了死后时间、材料冷藏和剪切应变依赖性的影响。本文描述了一种测量恒河猴体内大脑动态特性的装置，并给出了体内实验的初步数据。离体人脑动态剪切试验结果表明，储存模量g′在6 ~ 11 × 103dyn/cm2之间，损耗模量g″在3·5 ~ 6·0 × 103dyn/cm2之间，损耗tan δ在0·40 ~ 0·55之间。
Investigators have been studying the mechanical phenomena associated with impact to the head for many years. Several theories on the behavior of the brain during head impact have come from these studies but there has been a notable lack of information on the bulk mechanical properties of the brain which are necessary for the evaluation of these theories. This paper represents an initial attempt at providing such information.The dynamic complex shear modulus ofin vitrosamples of human brain have been measured. Specimens from eight brains have been subjected to a sinusoidal shear stress input under resonant conditions in an electro-mechanical test device. Tests were conducted to determine the effects of time after death, refrigeration of material and shear strain dependence. A device to measure the dynamic properties of brainin vivois described and preliminary data onin vivotests on Rhesus monkeys is presented.The results of the dynamic shear testing onin vitrohuman brain indicate that the storage modulusG′ lies between 6–11 × 103dyn/cm2, the loss modulusG″ lies between 3·5–6·0 × 103dyn/cm2and the loss tangent tan δ is in the range 0·40-0·55.