Is there a safety-net effect with computer-aided detection?
Is there a safety-net effect with computer-aided detection?
复制标题
DOI：
10.1117/1.jmi.7.2.022405
复制
发表时间：
2020-03-01
影响因子：
2.4
通讯作者：
Hulleman, Johan
中科院分区：
文献类型：
--
作者：
Du-Crow, Ethan;Astley, Susan M.;Hulleman, Johan
计算机辅助检测 (CAD) 系统用于帮助读者解读筛查性乳房 X 光检查。专业读者最初无需辅助即可搜索图像，然后再次借助 CAD 进行搜索，CAD 会提示自动检测到可疑区域。这可能会导致“安全网”效应，即最初的无辅助图像搜索会受到不利影响，因为它是使用 CAD 进行附加搜索的初步结果，因此可能不太彻底。为了研究这种效应的存在，我们为非专业观察者创建了一个视觉搜索实验，用 CAD 镜像乳房筛查。每个观察者在有提示（CAD）和无提示（无 CAD）条件下在合成图像中搜索 100 张图像中的微钙化簇。该研究招募了 52 名参与者，其中 48 名参与者的眼球运动被实时跟踪；其他 4 名参与者无法准确校准，因此仅收集行为数据。在 CAD 条件下，在显示提示之前，图像覆盖率显着低于无 CAD 条件下的覆盖率 (t(47) = 5.29，p < 0.0001）。对于由 CAD 标记的目标，观察者的敏感性显着高于无 CAD 条件下的相同目标 (t(51) = 6.56，p < 0.001）。对于未用 CAD 标记的目标，与无 CAD 条件下的相同目标相比，CAD 条件下的观察者灵敏度没有显着差异 (t(51) = 0.54，p = 0.59）。这些结果表明，最初的搜索可能会受到 CAD 随后可用性的影响；如果是这样，横断面 CAD 疗效研究在估计效益时应考虑到该效果。 (C) 2019 年光学光学仪器工程师协会 (SPIE)
Computer-aided detection (CAD) systems are used to aid readers interpreting screening mammograms. An expert reader searches the image initially unaided and then once again with the aid of CAD, which prompts automatically detected suspicious regions. This could lead to a "safety-net" effect, where the initial unaided search of the image is adversely affected by the fact that it is preliminary to an additional search with CAD and may, therefore, be less thorough. To investigate the existence of such an effect, we created a visual search experiment for nonexpert observers mirroring breast screening with CAD. Each observer searched 100 images for microcalcification clusters within synthetic images in both prompted (CAD) and unprompted (no-CAD) conditions. Fifty-two participants were recruited for the study, 48 of whom had their eye movements tracked in real-time; the other 4 participants could not be accurately calibrated, so only behavioral data were collected. In the CAD condition, before prompts were displayed, image coverage was significantly lower than coverage in the no-CAD condition (t(47) = 5.29, p < 0.0001). Observer sensitivity was significantly greater for targets marked by CAD than the same targets in the no-CAD condition (t(51) = 6.56, p < 0.001). For targets not marked by CAD, there was no significant difference in observer sensitivity in the CAD condition compared with the same targets in the no-CAD condition (t(51) = 0.54, p = 0.59). These results suggest that the initial search may be influenced by the subsequent availability of CAD; if so, cross-sectional CAD efficacy studies should account for the effect when estimating benefit. (C) 2019 Society of Photo Optical Instrumentation Engineers (SPIE)