New linear polyamine derivatives in spider venoms
New linear polyamine derivatives in spider venoms
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DOI：
10.1016/j.toxicon.2005.04.018
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发表时间：
2005-09-01
期刊：
影响因子：
2.8
通讯作者：
Bigler, L
中科院分区：
文献类型：
--
作者：
Tzouros, M;Chesnov, S;Bigler, L
Linear free polyamines were characterized in the venom of the spiders Agelenopsis aperta, Hololena curta, and Paracoelotes birulai by RP-HPLC coupled to mass spectrometry. The several linear polyamines found were tetramine, pentamine, and hexamine derivatives. Some of these natural products were identified as N-hydroxylated, guanidylated, or acetylated compounds. In addition, the biosynthetical pathway leading to the formation of acylpolyamines in spider venoms is discussed. (c) 2005 Elsevier Ltd. All rights reserved.
