Gas chromatography/multiphoton ionization Fourier transform mass spectrometry.
Gas chromatography/multiphoton ionization Fourier transform mass spectrometry.
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气相色谱/多光子电离傅里叶变换质谱。
DOI：
10.1021/ac00284a027
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发表时间：
1985
影响因子：
7.4
通讯作者：
Gross,ML
中科院分区：
文献类型：
--
作者：
Sack,TM;McCrery,DA;Gross,ML
对毛细管气相色谱仪/傅里勒变换质谱仪（GC/FTMS）进行了改进，使其能够使用266 nm波长的脉冲激光进行多光子电离（MPI）。MPI是一种选择性电离多种多环芳烃（PAHs）的方法，无论是在测试混合物中还是在汽油样品中，其选择性与前人的研究结果一致。然而，现在使用FT质谱仪而不是经常使用的飞行时间质谱仪，可以以大于20000 （fwhm）到m/z 200的质量分辨能力检测离子。据报道，几种多环芳烃的检测限在高（bbb20 000）和低（< 5000）分辨率下的低picogram范围内（即萘为7 pg），线性动态范围为2.5个数量级。质量测量精度也进行了评估，在中等分辨率和低离子密度下，发现典型误差约为1- 10ppm （5ppm）。气相色谱/质谱（GC/MS）结合了气相色谱强大的分离能力和质谱独特的定量和定性能力。由于这些特点，GC/MS已经成功地应用于涉及复杂混合物分析的无数问题。然而，GC/MS完全分离混合物中所有组分的能力是有限的，因为任何一种的“峰值容量”都是有限的
A capillary gas chromatograph/Fourler transform mass spectrometer (GC/FTMS) has been upgraded so that a pulsed laser operating at 266 nm can be used for multiphoton ioni-zation (MPI). MPI Is demonstrated to be a selective ioni-zation method for a variety of polycyclic aromatic hydrocarbons (PAHs) In both a test mixture and a sample of gasoline, and the selectivity is consistent with previous research. However, ions can now be detected at mass resolving powers of greater than 20000 (fwhm) up to m/z 200 by using the FT mass spectrometer rather than the often-used tlme-of-flight mass spectrometer. Detection limits for several of the PAHs are reported tobe in the low picogram range (ie, 7 pg for naphthalene) at both high (> 20 000) and low (< 5000) re-solving powers with a linear dynamic range of 2.5 orders of magnitude. Mass measurement accuracy is also evaluated, and thetypical errors are found to be approximately 1-10 ppm (5 ppm) at moderate resolving powers with low ion densities.Gas chromatography/mass spectrometry (GC/MS) com-bines thepowerful separation abilities of GC and the excep-tional quantitative and qualitative capabilities of mass spectrometry. Because of these features, GC/MS has been applied successfully to a myriad of problems involving the analysis of complex mixtures. However, there is a limit to the ability of GC/MS to separate completely allof the components in a mixture, because of the limited “peak capacity” of any