4. Adjusting for Time-Varying Confounding in Survival Analysis
4. Adjusting for Time-Varying Confounding in Survival Analysis
复制标题
4. 调整生存分析中的时变混杂因素
DOI:
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发表时间:
2004
期刊:
影响因子:
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通讯作者:
N. Verbitsky
中科院分区:
文献类型:
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作者:
Jennifer S. Barber;S. Murphy;N. Verbitsky
In this paper we illustrate how directly including endogenous time-varying confounders in the model of the effect of an exposure on a response can lead to bias in discrete time survival analysis. An alternative to this method is Hernán, Brumback, and Robins' (1999) use of sample weights to adjust for endogenous time-varying confounding. We discuss when this method can be used to provide unbiased estimators, and we illustrate the method by addressing a substantive research question using existing survey data. We also critically examine the robustness of the weighting method to violations of the underlying assumptions via a simulation analysis.
影响因子:
5.4
作者:
Hernán, MA;Brumback, B;Robins, JM
通讯作者:
Robins, JM