Metabolic Syndrome Among Adults in China: The 2010 China Noncommunicable Disease Surveillance
Metabolic Syndrome Among Adults in China: The 2010 China Noncommunicable Disease Surveillance
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DOI：
10.1210/jc.2016-2477
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发表时间：
2017-02-01
影响因子：
5.8
通讯作者：
Ning, Guang
中科院分区：
文献类型：
--
作者：
Lu, Jieli;Wang, Limin;Ning, Guang
内容：在中国，代谢综合征的患病率数据最近很少见。目的：本研究的目的是评估2010年代谢综合征及其组分的患病率。设计、设置和参与者：本研究覆盖了中国大陆所有31个省份，包括98，658名年龄≥ 18岁的中国成年人的全国代表性人群样本。其中，97，098名参与者符合此处报告的数据分析条件。主要结果测量：计算代谢综合征及其组分的患病率估计值。结果：代谢综合征的患病率为33.9%，其中男性为31.0%，女性为36.8%，表明我国约有4.54亿成年人患有代谢综合征。超过一半的成年人患有低高密度脂蛋白胆固醇（HDL-C），近一半的参与者患有高血压。腹部肥胖和低HDL-C在女性中比男性更普遍，而高血压、高血糖和高甘油三酯在男性中更常见。代谢综合征与一个较高的10年冠心病风险调整后的潜在危险因素和代谢综合征的每个组成部分作为连续variable.Conclusion：我们的研究结果表明，代谢综合征及其组成部分在中国大陆的一般成年人群的患病率很高。代谢综合征与10年内发生冠心病的高风险独立相关。
Context: In China, data on the prevalence of metabolic syndrome have been rare recently.Objective: The objective of the study was to evaluate the prevalence of metabolic syndrome and its components in 2010.Design, Setting, and Participants: The study covered all 31 provinces of mainland China and consisted of a nationally representative population sample of 98,658 Chinese adults aged >= 18 years. Of these, 97,098 participants were eligible for the data analysis reported here.Main Outcome Measures: Estimates of the prevalence of metabolic syndrome and its components were calculated. To further explore whether metabolic syndrome is associated with the 10-year coronary heart disease risk, sex-stratified logistic regression models were used.Results: The prevalence of the metabolic syndrome was 33.9% (31.0% in men and 36.8% in women), which indicates that metabolic syndrome affects approximately 454 million adults in China. More than half of total adult population was suffering from low high-density lipoprotein cholesterol (HDL-C), and nearly half of participants had high blood pressure. Abdominal obesity and low HDL-C were more prevalent in women than in men, whereas high blood pressure, high blood glucose, and high triglycerides were more common in men. Metabolic syndrome was associated with a higher 10-year coronary heart disease risk after adjustment for potential risk factors and each component of metabolic syndrome as continuous variables.Conclusion: Our results showed a high prevalence of metabolic syndrome and its components in the general adult population in mainland China. Metabolic syndrome was independently associated with a higher 10-year risk of developing coronary heart disease.