1,6-Addition of Tertiary Carbon Radicals Generated From Alcohols or Carboxylic Acids by Visible-Light Photoredox Catalysis
1,6-Addition of Tertiary Carbon Radicals Generated From Alcohols or Carboxylic Acids by Visible-Light Photoredox Catalysis
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DOI：
10.1021/acs.orglett.7b04034
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发表时间：
2018-02-02
期刊：
影响因子：
5.2
通讯作者：
Overman, Larry E.
中科院分区：
文献类型：
--
作者：
Abbas, Samir Y.;Zhao, Peng;Overman, Larry E.
由Ir催化的可见光光催化剂产生的叔碳自由基加成到缺电子的1，3-二烯以良好的产率进行，以将δ-取代的β，γ-不饱和羰基片段附加到叔醇或羧酸前体上，并构建新的季碳中心。
The addition of tertiary carbon radicals generated by an Ir-catalyzed visible-light photocatalyst to electron-deficient 1,3-dienes proceeds in good yields to append a delta-substituted beta,gamma-unsaturated carbonyl fragment to a tertiary alcohol or carboxylic acid precursor and construct a new quaternary carbon center.