Incorporating Salivary Biomarkers Into Nursing Research: An Overview and Review of Best Practices
Incorporating Salivary Biomarkers Into Nursing Research: An Overview and Review of Best Practices
复制标题
DOI：
10.1177/1099800412443892
复制
发表时间：
2012-10-01
影响因子：
2.5
通讯作者：
Schumann, Lynette Lau
中科院分区：
文献类型：
--
作者：
Granger, Douglas A.;Johnson, Sara B.;Schumann, Lynette Lau
唾液中存在的分析物和生物标记物可以深入了解环境化学暴露的个体差异、生殖激素的变化、治疗性和非法物质的使用、压力相关生理学的变化以及传染病的免疫足迹。唾液分析提供的丰富信息有潜力丰富生物行为护理研究，使研究人员能够在临床以及患者和参与者的日常社会世界中测量这些个体差异。在这篇文章中，作者为这个领域的新研究人员提供了一个路线图，他们希望更多地了解如何将唾液生物标本整合到下一代健康研究中。此外，作者强调了已经从事这一领域的研究人员避免常见陷阱的最佳实践和策略。
Analytes and biomarkers present in saliva may provide insight into individual differences in environmental chemical exposures, variation in reproductive hormones, therapeutic and illegal substance use, changes in stress-related physiology, and the immunologic footprints of infectious disease. The wealth of information provided by salivary analytes has the potential to enrich biobehavioral nursing research by enabling researchers to measure these individual differences in the clinic as well as in patients' and participants' everyday social worlds. In this article, the authors provide a roadmap for researchers new to this area who would like to learn more about integrating salivary biospecimens into the next generation of health research. In addition, the authors highlight best practices and strategies to avoid common pitfalls for researchers already engaged in this field.