Preoperative sensorimotor mapping in brain tumor patients using spontaneous fluctuations in neuronal activity imaged with functional magnetic resonance imaging: initial experience.
Preoperative sensorimotor mapping in brain tumor patients using spontaneous fluctuations in neuronal activity imaged with functional magnetic resonance imaging: initial experience.
复制标题
使用功能性磁共振成像成像的神经元活性中的自发波动在脑肿瘤患者中的术前感官图：初始体验。
DOI：
10.1227/01.neu.0000350868.95634.ca
复制
发表时间：
2009-12
期刊：
影响因子：
4.8
通讯作者：
Shimony JS
中科院分区：
文献类型：
--
作者：
Zhang D;Johnston JM;Fox MD;Leuthardt EC;Grubb RL;Chicoine MR;Smyth MD;Snyder AZ;Raichle ME;Shimony JS
描述静息状态相关标测作为脑肿瘤切除术术前计划潜在辅助手段的初步经验。静息状态血氧依赖（BOLD）的功能磁共振成像获得了17名健康的年轻人和4例脑肿瘤侵犯感觉运动皮层。常规fMRI运动映射（手指敲击协议）也进行了患者。术中，运动手区映射使用皮层刺激。使用静息状态BOLD数据获得了感觉运动皮层的稳健和一致的描绘。静息状态功能映射的患者显示定位到感觉运动区与皮层刺激映射（CSM）一致，并在所有情况下执行以及或优于基于任务的功能磁共振成像。静息状态相关映射是一种可靠的功能定位的工具。这种方法相比，以及与“金标准”CSM和传统的运动映射功能磁共振成像相比，提供了几个优势。
To describe initial experience with resting state correlation mapping as a potential aid for presurgical planning of brain tumor resections. Resting state blood oxygenation dependent (BOLD) fMRI was acquired in seventeen healthy young adults and four patients with brain tumors invading sensorimotor cortex. Conventional fMRI motor mapping (finger tapping protocol) was also performed in the patients. Intraoperatively, motor hand area was mapped using cortical stimulation. Robust and consistent delineation of sensorimotor cortex was obtained using the resting state BOLD data. Resting state functional mapping in patients showed localization to sensorimotor areas consistent with cortical stimulation mapping (CSM) and in all cases performed as well or better than task-based fMRI. Resting state correlation mapping is a promising tool for reliable functional localization of eloquent cortex. This method compares well with “gold standard” CSM and offers several advantages in comparison to conventional motor mapping fMRI.