Clock network in Drosophila
Clock network in Drosophila
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DOI：
10.1016/j.cois.2014.11.003
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发表时间：
2015-02-01
影响因子：
5.3
通讯作者：
Helfrich-Foerster, Charlotte
中科院分区：
文献类型：
--
作者：
Hermann-Luibl, Christiane;Helfrich-Foerster, Charlotte
生物钟由所有动物大脑中的肽能神经元网络组成。这种肽能网络的功能已在很大程度上揭示了果蝇（Drosophila melanogaster），这是由于相对较少的具有良好特征的时钟神经元，并且这些神经元可以被遗传操纵。在这里，我们回顾了昼夜节律网络的神经元组织和单个时钟神经元和神经肽在其中的作用。
The circadian clock consists of a network of peptidergic neurons in the brain of all animals. The function of this peptidergic network has been largely revealed in the fruit fly Drosophila melanogaster due to the relatively few well characterized clock neurons and because these neurons can be genetically manipulated. Here we review the neuronal organization of the circadian network and the role of individual clock neurons and neuropeptides in it.