Chemical Constituents of the Roots of Anemone altaica Fisch. ex C. A. Mey.
Chemical Constituents of the Roots of Anemone altaica Fisch. ex C. A. Mey.
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DOI：
10.1111/j.1744-7909.2005.00147.x
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发表时间：
2005-09
影响因子：
11.4
通讯作者：
Zhong-jie Zou;Yuesheng Dong;Jun-shan Yang
中科院分区：
文献类型：
--
作者：
Zhong-jie Zou;Yuesheng Dong;Jun-shan Yang
摘要：阿尔泰银莲花菲施的根. ex C. A. Mey.长期以来，在中国民间医药中用于治疗癫痫、神经衰弱和关节炎。为了寻找新的具有生物活性的化合物，对黄芪根的化学成分进行了研究。从该植物的乙醇提取物中分离得到9个化合物。根据光谱方法鉴定了这些化合物的结构，分别为4-（9 H-β-咔啉-1-基）-4-氧代丁酸（1）、异阿魏酸羧甲基酯（2）、β-异阿魏酸（3）、蓟醛（4）、5-羟基-4-氧代戊酸（5）、三十烷（6）、棕榈酸（7）、β-谷甾醇（8）和胡萝卜苷（9）。其中1和2为新化合物，3和4为首次从该属植物中分离得到。（责任编辑：王伟）
Abstract: The roots of Anemone altaica Fisch. ex C. A. Mey. have been used in the treatment of epilepsia, neurasthenia, and arthritis in Chinese folk medicine for a long time. In order to find new and bioactive compounds, the chemical constituents of the roots of A. altaica were investigated and nine compounds were isolated from the EtOH extract of this plant. On the basis of spectroscopic methods, the structures of these compounds were elucidated as 4-(9H-β-carbolin-1-yl)-4-oxo-butyric acid (1), carboxymethyl isoferulate (2), β isoferulic acid (3), cirsiumaldehyde (4), 5-hydroxy-4-oxo-pentanoic acid (5), triacontane (6), palmic acid (7), β-sitosterol (8), and daucosterol (9). Among them, 1 and 2 were new compounds, and 3 and 4 were obtained from this genus for the first time. (Managing editor: Wei WANG)