Household risk factors for Trypanosoma cruzi seropositivity in two geographic regions of Ecuador
Household risk factors for Trypanosoma cruzi seropositivity in two geographic regions of Ecuador
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DOI：
10.1645/ge-899r.1
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发表时间：
2007-02-01
影响因子：
1.3
通讯作者：
Grijalva, Mario J.
中科院分区：
文献类型：
--
作者：
Black, Carla L.;Ocana, Sofia;Grijalva, Mario J.
在厄瓜多尔，很少有关于环境因素与克氏锥虫传播之间关系的研究。我们进行了一项横断面研究的家庭危险因素的T。在厄瓜多尔的两个不同的地理区域，克氏血清阳性。通过家庭调查收集暴露信息，并对受试者进行T血清学证据检测。克氏感染总共纳入了来自997个家庭的3，286名受试者。在沿海地区，与血清阳性相关的因素是住在棕榈屋顶的房子里（比值比[OR] = 2.63，95%置信区间，[1.61，4.27]），木墙（OR = 5.75 [2.04，16.18]）或藤壁（OR = 2.81 [1.31，6.04]），以及围隔中存在木柴（OR = 2.48 [1.54，4.01]）。家外垃圾堆积与血清阳性风险降低相关（OR = 0.25 [0.12，0.51]）。在安第斯地区，住在土坯墙的房子里是克氏锥虫血清阳性的唯一预测因素。结论：T.克鲁齐病在厄瓜多尔的传播因地理区域而异，可能是因为锥蝽病媒物种在每个区域的行为不同。对T.在特定地区开展克氏锥虫病的研究对于在这些地区制定有效的南美锥虫病控制战略是必要的。
Few studies on the relationship between environmental factors and Trypanosoma cruzi transmission have been conducted in Ecuador. We conducted a cross-sectional study of household risk factors for T. cruzi seropositivity in 2 distinct geographical regions of Ecuador. Exposure information was collected via household surveys, and subjects were tested for serological evidence of T. cruzi infection. In total, 3,286 subjects from 997 households were included. In the coastal region, factors associated with seropositivity were living in a house with a palm roof (odds ratio [OR] = 2.63, 95% confidence interval, [1.61, 4.27]), wood walls (OR = 5.75 [2.04, 16.18]), or cane walls (OR = 2.81 [1.31, 6.04]), and the presence of firewood in the peridomicile (OR = 2.48 [1.54, 4.01]). Accumulation of trash outside the home was associated with a reduced risk of seropositivity (OR = 0.25 [0.12, 0.51]). In the Andean region, living in a house with adobe walls was the only factor predictive of T cruzi seropositivity. In conclusion, risk factors for T. cruzi transmission in Ecuador varied by geographic region, probably because of differing behavior of the triatomine vector species in each region. An understanding of the transmission dynamics of T. cruzi in a particular area is necessary for the development of effective Chagas disease control strategies in those areas.