Fatal subacute cytomegalovirus encephalitis associated with hypogammaglobulinemia and thymoma
Fatal subacute cytomegalovirus encephalitis associated with hypogammaglobulinemia and thymoma
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DOI：
10.4065/78.2.223
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发表时间：
2003-02-01
影响因子：
8.9
通讯作者：
King, D
中科院分区：
文献类型：
--
作者：
Cucchiara, BL;Forman, MS;King, D
副胸腺综合征是与胸腺瘤相关的全身性疾病。 Good 于 1954 年首次发现了这样一种副心境综合征，即低丙种球蛋白血症，并被称为 Good 综合征。由于相关的免疫缺陷，患有这种综合征的患者会出现各种反复感染。我们描述了一名与 Good 综合征相关的巨细胞病毒脑炎患者，并讨论了尸检的病理结果。巨细胞病毒感染的可能性应该是。如果存在适当的临床症状，则应在评估 Good 综合征患者时尽早考虑。
Parathymic syndromes are systemic disorders that occur in association, with thymoma. One such parathymic syndrome, hypogammaglobulinemia, was initially identified by Good in 1954 and has been referred to as Good syndrome. Patients with this syndrome develop a variety of recurrent infections due to the associated immunodeficiency. We describe a patient with cytomegalovirus encephalitis associated with Good syndrome and discuss the pathologic findings present on autopsy. The possibility of a cytomegalovirus infection should. be considered early in the evaluation of patients with Good syndrome if appropriate clinical symptoms are present.