Effect of hand hygiene on infectious disease risk in the community setting: A meta-analysis
Effect of hand hygiene on infectious disease risk in the community setting: A meta-analysis
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DOI：
10.2105/ajph.2007.124610
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发表时间：
2008-08-01
影响因子：
12.7
通讯作者：
Larson, Elaine L.
中科院分区：
文献类型：
--
作者：
Aiello, Allison E.;Coulborn, Rebecca M.;Larson, Elaine L.
为了量化手卫生干预措施对胃肠道和呼吸道疾病发病率的影响，并确定提供最大疗效的干预措施，我们搜索了从1960年1月到2007年5月发表的4个手卫生试验电子数据库，并进行了荟萃分析，以生成干预措施(N=30项研究)的汇集比率。手卫生干预措施的改善导致胃肠道疾病减少了31%(95%可信区间=19%，42%)，呼吸道疾病减少了21%(95%可信区间=5%，34%)。最有益的干预措施是使用非抗菌肥皂进行手卫生教育。与使用非抗菌肥皂相比，使用抗菌肥皂几乎没有额外的好处。卫生显然对胃肠道感染有效，在较小程度上也能预防呼吸道感染。需要研究检查呼吸道疾病期间的卫生做法和针对气雾剂传播的干预措施。
To quantify the effect of hand-hygiene interventions on rates of gastrointestinal and respiratory illnesses and to identify interventions that provide the greatest efficacy, we searched 4 electronic databases for hand-hygiene trials published from January 1960 through May 2007 and conducted meta-analyses to generate pooled rate ratios across interventions (N = 30 studies).Improvements in hand hygiene resulted in reductions in gastrointestinal illness of 31% (95% confidence intervals [CI] = 19%, 42%) and reductions in respiratory illness of 21% (95% CI = 5%, 34%). The most beneficial intervention was hand-hygiene education with use of nonantibacterial soap. Use of antibacterial soap showed little added benefit compared with use of nonantibacterial soap.Hand hygiene is clearly effective against gastrointestinal and, to a lesser extent, respiratory infections. Studies examining hygiene practices during respiratory illness and interventions targeting aerosol transmission are needed.