Ene reactions of acyl nitroso intermediates with alkenes and their halocyclization
Ene reactions of acyl nitroso intermediates with alkenes and their halocyclization
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DOI：
10.1016/j.tetlet.2004.10.128
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发表时间：
2004-12-13
影响因子：
1.8
通讯作者：
Tsutsumi, K
中科院分区：
文献类型：
--
作者：
Fakhruddin, A;Iwasa, S;Tsutsumi, K
过渡金属催化异羟肟酸1a-b的过氧化氢氧化生成高活性的酰基亚硝基中间体，这些过渡物种被烯烃2a-c捕获，得到相应的烯产品3a-d和4b，产率高达91%，而3d的卤代环化反应以77%的产率得到取代恶唑烷酮5a。(C)2004爱思唯尔有限公司。保留所有权利。
Highly reactive acyl nitroso intermediates were formed in situ by transition metals-catalyzed hydrogen peroxide oxidation of hydroxamic acids 1a-b and these transient species trapped with alkenes 2a-c to afford the corresponding ene products 3a-d and 4b up to 91% yield, and halocyclization of 3d gave substituted oxazolidinone 5a in 77% yield. (C) 2004 Elsevier Ltd. All rights reserved.