Maturation of visual evoked potentials across adolescence

Maturation of visual evoked potentials across adolescence
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DOI:
10.1016/j.braindev.2011.10.009
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发表时间:
2012-09-01
影响因子:
1.7
通讯作者:
McArthur, Genevieve
McArthur, Genevieve
中科院分区:
医学4区
文献类型:
--
作者:
Mahajan, Yatin;McArthur, Genevieve

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青春期是由童年向成年过渡的时期,其特点是大脑结构和功能发生重大变化。我们研究了整个青春期大脑视觉处理功能的变化。对90名青少年(10 ~ 18岁)和10名成人进行了三种模式反转棋盘刺激的视觉诱发电位(vep)测量。在整个青春期,N75和P100 VEP峰的大小减小,而N135峰的大小略有增加。VEP峰值的潜伏期在整个青春期没有可靠的变化。结果表明,即使是非常基本的视觉感觉功能也会在整个青春期持续发展。结果表明,在整个青春期,视觉副细胞和大细胞通路发生了显著变化。(C) 2011日本儿童神经病学学会。Elsevier B.V.版权所有。
Adolescence represents the period of transition from childhood to adulthood and is characterized by significant changes in brain structure and function. We studied changes in the functional visual processing in the brain across adolescence. Visual evoked potentials (VEPs) to three types of pattern reversal checkerboard stimuli were measured in 90 adolescents (10-18 years) and 10 adults. Across adolescence, the N75 and P100 VEP peaks decreased in size while the N135 peak increased slightly in size. The latency of VEP peaks showed no reliable change across adolescence. The results suggest that even very basic visual sensory function continues to develop throughout adolescence. The results indicate significant changes in visual parvocellular and magnocellular pathways across adolescence. (C) 2011 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.