GENOMIC ORGANIZATION OF HUMAN HISTO-BLOOD GROUP ABO GENES
GENOMIC ORGANIZATION OF HUMAN HISTO-BLOOD GROUP ABO GENES
复制标题
DOI：
10.1093/glycob/5.1.51
复制
发表时间：
1995-02-01
期刊：
影响因子：
4.3
通讯作者：
HAKOMORI, S
中科院分区：
文献类型：
--
作者：
YAMAMOTO, F;MCNEILL, PD;HAKOMORI, S
我们已经分离出包含30 kbp的组织血型ABO基因座的人类基因组DNA克隆。外显子的位置已被映射，外显子-内含子边界的核苷酸序列已被确定。人类ABO基因由至少7个外显子组成，7个编码外显子中的编码序列跨越基因组DNA的18 kb以上，外显子大小范围为28 - 688 bp，大部分编码序列位于外显子7。
We have isolated human genomic DNA clones encompassing 30 kbp of the histo-blood group ABO locus. The locations of the exons have been mapped and the nucleotide sequences of the exon-intron boundaries have been determined. The human ABO genes consist of at least seven exons, and the coding sequence in the seven coding exons spans over 18 kb of the genomic DNA, The exons range in size from 28 to 688 bp, with most of the coding sequence lying in exon 7.