An Ultra-miniaturized Near Infrared Spectroscopy System to Assess Sleep Apnea in Children with Down Syndrome.
An Ultra-miniaturized Near Infrared Spectroscopy System to Assess Sleep Apnea in Children with Down Syndrome.
复制标题
用于评估唐氏综合症儿童睡眠呼吸暂停的超小型近红外光谱系统。
DOI：
10.1109/embc.2018.8513038
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
Bozkurt,Alper
中科院分区：
文献类型：
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作者：
Beppler,EricC;Dieffenderfer,James;Songkakul,Tanner;Krystal,Andrew;Bozkurt,Alper
唐氏综合症是干扰正常和健康睡眠的健康疾病之一。大多数患有唐氏综合症的儿童都会被转诊至睡眠诊所，以评估其呼吸暂停的严重程度。对于这一敏感的患者群体来说，基于定期多导睡眠图的呼吸暂停评估一直具有挑战性。我们展示了我们在开发一种柔性创可贴大小的近红外光谱系统 (pediBand) 方面所做的努力，用于唐氏综合症儿童呼吸暂停的家庭评估。结合惯性测量单元，pediBand 记录心率、心率变异性、呼吸频率、动脉血氧饱和度和脑血氧饱和度。这些是评估睡眠呼吸暂停的基本参数，也可用于评估一般睡眠表现。改良版的pediBand系统在成年患者身上进行了评估，并成功证明了睡眠呼吸暂停引发的血流动力学系统的变化。
Down syndrome is one of the health disorders that interferes with regular and healthy sleep. Most children with Down syndrome are referred to a sleep clinic for the assessment of the severity of their apnea. Regular polysomnography based assessment of apnea has been challenging with this sensitive patient population. We present our efforts towards developing a flexible adhesive bandage sized near infrared spectroscopy system (pediBand) for home-assessment of apnea in children with Down syndrome. Combined with inertial measurement units, pediBand record heart rate, heart rate variability, respiratory rate, arterial oxygen saturation and cerebral oxygen saturation. These are the essential parameters to assess sleep apnea and could also potentially be used in the assessment of sleep performance in general. A modified version of pediBand system was evaluated on adult patients and successfully demonstrated the changes in hemodynamic system triggered by sleep apnea.