Invasive primary cutaneous phycomycosis in diabetic leg ulcers.
Invasive primary cutaneous phycomycosis in diabetic leg ulcers.
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糖尿病腿部溃疡的侵袭性原发性皮肤藻真菌病。
DOI：
10.1001/archsurg.1980.01380060068020
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发表时间：
1980
影响因子：
--
通讯作者：
Joseph F. Tomashefski
中科院分区：
文献类型：
--
作者：
J. W. Tomford;Diana Whittlesey;Jerrold J. Ellner;Joseph F. Tomashefski
两例糖尿病腿部溃疡形式的皮肤藻真菌病通过培养和活检证实侵袭性真菌感染被诊断出来。第一位患者有感染的水疱性皮肤病变。全身两性霉素 B 治疗和反复清创可治愈。第二名患者在高血糖和肾功能不全的情况下出现外伤后腿部溃疡。严重的感染需要进行治疗性截肢。藻菌可引起糖尿病腿部溃疡或使其复杂化，此类感染可能需要活检才能早期识别和随后的成功治疗。
Two cases of cutaneous phycomycosis in the form of diabetic leg ulcers were diagnosed by culture and biopsy demonstration of invasive fungal infection. The first patient had an infected vesicular skin lesion. Systemic amphotericin B therapy and repeated debridement were curative. A posttraumatic leg ulcer developed in the second patient in the setting of hyperglycemia and renal insufficiency. Aggressive infection necessitated a curative amputation. Phycomycetes can cause or complicate diabetic leg ulcers and such infections may require biopsy for early recognition and subsequent successful therapy.