Coronary Angiography Characteristics of Symptomatic Patients with Prior Coronary Artery Bypass Graft: A Descriptive Study.
Coronary Angiography Characteristics of Symptomatic Patients with Prior Coronary Artery Bypass Graft: A Descriptive Study.
复制标题
既往接受过冠状动脉搭桥术的有症状患者的冠状动脉造影特征：一项描述性研究
DOI：
10.1155/2019/1832128
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发表时间：
2019-01-01
影响因子：
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通讯作者：
Wang, Jiangang
中科院分区：
文献类型：
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作者：
Ma, Xiaolong;Chen, Pengfei;Wang, Jiangang
目的探讨冠状动脉旁路移植术（CABG）后有症状患者的冠状动脉造影特点。方法选取2009年至2017年在北京安贞医院行冠状动脉旁路移植术但术后症状复发的患者993例，根据治疗方法分为药物治疗组（MT组）351例和经皮冠状动脉介入治疗组（PCI组）642例。对两组患者的临床资料进行分析。结果MT组患者年龄较大，合并慢性肺部疾病的可能性较大（6.6% vs3.4%，P=0.026），PCI组患者既往MI的可能性较大（8.8% vs17.0%，P < 0.001）。MT组54.4%的患者有移植物和自体冠状动脉新发病变，而PCI组为58.1%（P=0.003）; MT组80.6%的患者有C型冠状动脉病变，而PCI组为60.1%（P < 0.001）。MT组冠状动脉弥漫性病变的比例明显高于MT组（49.3%比15.0%，P < 0.001）。结论接受MT治疗的患者（35.3%）可能存在桥血管闭塞和以弥漫性病变为特征的C型冠状动脉病变。
Objectives The target of this study was to explore the coronary angiography characteristics for symptomatic patients with prior coronary artery bypass graft (CABG). Methods Between 2009 and 2017, 993 patients who had undergone CABG but subsequently suffered recurrent symptoms in Beijing Anzhen Hospital were selected for this study and divided into either medical therapy (MT) group (n = 351) or percutaneous coronary intervention (PCI) group (n = 642) based on the treatment. Clinical data were analyzed between two groups. Results Patients in the MT group were older and more likely to have chronic lung disease (6.6% vs 3.4%, P=0.026) while patients in the PCI group were more likely to have prior MI (8.8% vs 17.0%, P < 0.001). In the MT group, 54.4% of patients had newly developed lesions both in the graft and native coronary artery while 58.1% in the PCI group (P=0.003), and in the MT group, 80.6% had type C coronary artery disease while 60.1% in the PCI group (P < 0.001). Patients in the MT group presented higher proportion of diffuse lesions (49.3% vs 15.0%, P < 0.001) in native coronary arteries. Conclusion Patients receiving MT (35.3%) likely had occluded grafts and type C coronary artery disease featuring as diffuse lesions.