Small intestinal morphometric and biomechanical changes during physiological growth in rats
Small intestinal morphometric and biomechanical changes during physiological growth in rats
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DOI：
10.1016/j.jbiomech.2004.04.025
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发表时间：
2005-03-01
影响因子：
2.4
通讯作者：
Gregersen, H
中科院分区：
文献类型：
--
作者：
Lu, X;Zhao, JB;Gregersen, H
研究了1 ~ 32周龄大鼠生理生长过程中小肠几何形状、残余应变和应力-应变特性的变化。小肠体积和尺寸随年龄增长而增加，单位长度重量随年龄增长而增加5倍，肠壁截面积随年龄增长而增加4倍。零应激状态下十二指肠开口角在出生后第1周和第2周分别约为220度和290度，其余年龄十二指肠开口角均降至170度（p < 0.005）。回肠开口角度在120 ~ 150度之间。十二指肠黏膜表面残余应变随年龄变化不大（p < 0.05），回肠黏膜表面残余应变随年龄变化而降低（p < 0.05）
Changes in small intestinal geometry, residual strain and stress-strain properties during physiological growth were studied in rats ranging from 1 to 32 weeks of age. Small intestinal mass and dimensions increased many-fold with age, e.g. the weight per unit length increased five-fold with age and the wall cross-sectional area increased four-fold. The opening angle of duodenum obtained at zero-stress state was approximately 220degrees and 290degrees during the first and second week after birth and decreased to 170degrees at other ages (p < 0.005). The opening angle of ileum ranged between 120degrees and 150degrees. The residual strain of duodenum at the mucosal surface did not vary with age (p > 0.05) whereas the residual strain of ileum at the mucosal surface decreased with age (p