CHRONIC PULMONARY INSUFFICIENCY OF PREMATURITY (CPIP)
CHRONIC PULMONARY INSUFFICIENCY OF PREMATURITY (CPIP)
复制标题
早产儿慢性肺功能不全 (CPIP)
作者：
A. Krauss;D. B. Klain;Peter A. M. Auld
这份报告的目的是描述一种发生在早产儿的延迟性呼吸窘迫综合征，通常在1250克以下。在出生的时候。与透明膜病(HMD)不同，这种综合征在以前健康的婴儿出生5-10天后发生；与HMD不同，它持续2-4周。慢性早产儿肺功能不全(CPIP)的死亡率为10%-20%。婴儿经常出现呼吸暂停，需要补充氧气，但缺乏HMD、支气管肺发育不良、Wilson-Mikity综合征或氧气中毒的典型放射学表现。与体重在1250克以下的健康婴儿相比。出生时患有CPIP的婴儿表现出以下异常：恢复通常在60天内完成。在CPIP开始前的5-10天内，对CPIP的认识可以消除错误的安全感，这种安全感通常会传达给焦虑的父母。CPIP和HMD在生理上的相似性提示CPIP的病因缺乏表面活性物质。
The purpose of this report is to describe a syndrome of delayed respiratory distress occurring in premature infants, usually under 1250 gms. at birth. Unlike hyaline membrane disease (HMD), this syndrome occurs after 5-10 days of life in a previously healthy infant; unlike HMD it persists for 2-4 weeks. Chronic pulmonary insufficiency of prematurity (CPIP) carries a 10-20% mortality. The infants are frequently apneic and require supplemental oxygen, but lack the characteristic radiologic findings of HMD, bronchopulmonary dysplasia, Wilson-Mikity syndrome, or oxygen toxicity. Compared to healthy infants under 1250 gm. at birth (nl) infants with CPIP demonstrate the following abnormalities:Recovery is usually complete in 60 days. An awareness of CPIP can eliminate a false sense of security, often communicated to anxious parents, during the 5-10 day period before the onset of CPIP. The physiologic similarity between CPIP and HMD suggests lack of surfactant as the etiology of CPIP.